Rashin lafiyar bacci da aka haɗa da matakan neurotransmitters
Yawancin tsarin atrophy (MSA) cuta ce mai saurin kamuwa da cuta mai rauni wanda kusan kullum tana tare da mummunan bacci. Akwai shaidun asibiti cewa wasu daga cikin matsalolin bacci da ke da alaƙa da wannan yanayin za a iya kwantar da su ta hanyar magungunan da ke maye gurbin gurɓatar dopamine.
Don bincika wannan binciken na asibiti, masu bincike daga Jami'ar Michigan sun yi nazarin ƙwaƙwalwar ƙwaƙwalwar ƙwaƙwalwar ƙwaƙwalwar marasa lafiya na 13 tare da batutuwan kula da lafiya na XAXX.
Abubuwan rediyo masu aiki waɗanda suka haɗu musamman don sunadarai a cikin dopamine da acetylcholine da ke samar da ƙwayoyin suna gudana ga mahalarta. Daga nan sai kwakwalwar ta yin amfani da kwayoyin halittar tomography (PET) da kuma walimar amfani da kwayar halitta guda daya.
An gudanar da sikanin ne a cikin dare biyu na polysomnography, wanda ya ƙunshi ci gaba da rikodin takamaiman masu canjin yanayi a lokacin bacci. Sakamakon binciken da aka samu daga PET da SPECT sun daidaita tare da rikodin polysomnography.
Sakamakon binciken ya nuna cewa marasa lafiya na MSA suna da ƙananan ƙarfi na dopamine da acholcholine masu samar da jijiyoyi fiye da abubuwan sarrafawa na yau da kullun. Lowerarancin ƙarancin waɗannan ƙwayoyin samar da ƙwaƙwalwar ƙwayar cuta, mafi muni ga matsalolin batutuwan.
Dopamine mai lalacewa da ke samar da jijiyoyi a cikin mahaɗa na kwakwalwa yana da alaƙa da alamun tsawa, magana da tashin hankali yayin barci. Sabanin haka, marasa lafiya waɗanda ke da mafi ƙasƙanci matakan samar da jijiyoyin acetylcholine a cikin ƙwaƙwalwar ƙwaƙwalwa suna da ƙarin katsewa a cikin numfashi yayin bacci.
Masu binciken sun kuma lura da cewa sassan kwakwalwa da ke sarrafa tsokoki na babban hanyar sama da harshe suna da alaƙa da mafi girma rashi a cikin ƙwayoyin acetylcholine.
Marubutan sun kammala da cewa rashin daidaiton sunadarai a cikin kwakwalwa na iya zama wani bangare na rikice-rikicen bacci, amma ana buƙatar ƙarin bincike don tabbatar da waɗannan binciken a cikin in ba haka ba lafiyayyun mutane da sauran raunin jijiyoyin jiki.
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