Prog Neuropsychopharmacol Biol Psychiatry. 2019 Jun 27: 109680. doi: 10.1016 / j.pnpbp.2019.109680.
Kim H1, Kim YK2, Lee JY3, Choi AR3, Kim DJ4, Choi JS5.
Abstract
Kev ua si hauv Internet gaming (IGD) tau dhau los ua rau kev txhawj xeeb loj hlob raws li tus cwj pwm uas muaj yees thiab tau muab piv nrog kev quav tshuaj / kev quav yeeb quav tshuaj. Txawm hais tias IGD pom kev kuaj mob thiab kev sib txawv, kev kho cov neurobiological hauv IGD tsis tau meej meej elucidated. Peb siv 18F-fluorodeoxyglucose PET los soj ntsuam qhov sib txawv ntawm cov kabmob metabolism thiab metabolic connectivity rau cov tub ntxhais hluas [peb caug rau cov neeg mob IGD, nees nkaum rau cov neeg mob uas siv cawv tsis zoo (AUD) thiab peb caug-cuaj noj qab nyob zoo (HC)]. Muab piv rau HC, IGD tau qhia tias hypometabolism nyob rau hauv sab nrauv cingulate cortex (ACC), lub cev ntu, pav ntaws, parietal thiab striatum thiab AUD pom cov hypometabolism hauv lub cev, lub cev thiab cov parietal lobule. Tsis tas li ntawd, IGD pom cov kev sib raug zoo ntawm ACC thiab kev ua si ntev thiab nruab nrab ntawm kev cog qoob loo orbitofrontal thiab impulsivity. Ntxiv thiab, IGD tau txo cov metabolic linkivity ntawm thaj tsam ntawm lub cev thiab limbic thiab nruab nrab ntawm qhov chaw tsav tsheb thiab cov cheeb tsam ntawm oxipital. Thiab AUD pom ntau dua metabolic connectivity ntawm thaj tsam orbitofrontal thiab parietal, thiab nruab nrab ntawm cov somatosensory los yog parietal thiab temporal regions, tab sis nqes metabolic txuas rau hauv cov cheeb tsam hauv frontoatal lossis fronto-limbic. Peb cov qhabnias tau muab pov thawj tias hypometabolism thiab hloov kho metabolic hauv IGD tej zaum yuav muaj feem xyuam nrog qhov txawv txav kev ua haujlwm ntev los ntawm kev ua si ntev ntev thiab kev ua haujlwm ntawm kev tsis txaus ntseeg / kev txhawb zog.
KEYWORDS: Kev haus cawv tsis zoo; Cov metabolism hauv plab; Kev ua si hauv Internet gaming; Metabolic connectivity; Positron emission tomography
PMID: 31255649
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