Okwu: nyocha omumu ohuru nke na egosi ikwuputa androgen receptor na oke oke agwo. Ọmụmụ ahụ hụrụ ndị nabatara na-alaghachi ịdị nkịtị site na awa 72, mana inwe mmekọahụ zuru oke na-ewe ụbọchị 15 iji laghachichaa. Ihe ndi ozo aghaghi itinye aka na nmekorita nke nmekorita nke nmekorita nke nmekorita nke 15
Romano-Torres M, Phillips-Farfán BV, Chavira R, Rodríguez-Manzo G, Fernández-Guasti A.
Neuroendocrinology. 2007; 85 (1): 16-26. Epub 2007 Jan 8.
Ngalaba Pharmacobiology, Centro de Investigación y Estudios Avanzados, Mexico City, Mexico.
ABSTRACT
N'oge na-adịbeghị anya, anyị gosipụtara na 24 h mgbe copulation to satiety, enwere mbelata ngbanye androgen receptor density (ARd) na mpaghara preoptic medial (MPOA) na mpaghara ventromedial hypothalamic nucleus (VMH), mana obughi ya bu n’elu bed nke the trea teralis (BST).
Enyocha ọmụmụ ihe ugbu a iji nyochaa ma ARd ọ gbanwee ebe ndị a na ụbụrụ ndị ọzọ, dịka amygdala (MeA) na mpụta larịị, akụkụ akụkụ (LSV), jikọtara ya na mgbanwe n'omume mmekọahụ na-esite n'iso nwanyi na-enwe mmekọahụ.
Ejiri ụmụ oke nwoke chụọ 48 h, 72 h ma ọ bụ 7 ụbọchị mgbe satiety mmekọahụ (4 h ad libitum copulation) iji chọpụta ARd site na immunocytochemistry; Ọzọkwa, a tụtara ọkwa testosterone n'ụdị otu nọọrọ onwe ha chụrụ ihe n'otu oge. Na nnwale ọzọ, a nwalere ụmụ nwoke maka mgbake omume mmekọahụ 48 h, 72 h ma ọ bụ 7 ụbọchị mgbe satiety nke mmekọahụ gasịrị. Nsonaazụ gosipụtara na 48 h mgbe nwute mmekọahụ 30% nke ụmụ nwoke gosipụtara otu ejaculation na 70% fọdụrụ gosipụtara ihe mgbochi zuru oke nke omume mmekọahụ..
Mbelata nke omume mmekọahụ na mgbakwunye ARd bụ naanị na akụkụ ntụgharị uche MPOA (MPOM). Abalị iri asaa na asaa mgbe agụụ mmekọahụ gasịrị, enwere mgbake nke inwe mmekọahụ yana mmụba ARD iji jikwaa ọkwa dị na MPOM yana oke mmechi nke ARd na LSV, BST, VMH na MeA.
Ejikọtaghị ọkwa testosterone n'ọbara oge satiety. A tụlere nsonaazụ ya na ndabere nke myirịta na ọdịiche dị n'etiti ARd na mpaghara ụbụrụ kpọmkwem na akparamagwa nwoke.
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