Behav Neurosci. 2013 Jun;127(3):458-64. doi: 10.1037/a0032332.
Garduño-Gutiérrez R, Guadarrama-Bazante L, León-Olea M, Rodríguez-Manzo G.
Source
Departamento de Farmacobiología, Cinvestav Sede Sur, Cinvestav Sede Sur, México City, México.
nkịtị
Ejaculation na-akwalite mwepụta opioid endogenous. Ntinye obi uto na-eme ka otutu agwa na mgbanwe mgbanwe omume na-adịgide adịgide, nke ihe mmachi mmekọrịta nwoke na nwanyị na-adịgide adịgide na oke ịpersụ ọgwụ na-achịkwa kachasị na-akpachapụ anya. Nihi na iwepu ume ngwu gunyere otutu okwu ejuputa, ya na oru a anyi huru na endogenous opioids weputara site na otutu ejaculations n'oge nmeghari ahu rue usoro ike gwurita onwe ha nwere ike idoghari mgbanwe mgbanwe nke inwe mmeko nwoke. Iji nwalee hypothesis a, etinyere oke oke nwoke nwere mmekọahụ na opioid receptor antagonist naltrexone tupu nkụda mmụọ wee nwalee ya maka omume mmekọahụ ma ọ bụ ọgwụ ọgwụ 24 h mgbe e mesịrị. A na-enyocha nke ikpeazụ site n'ọdịdị nke ihe nrịba ọnụnọ nke serotonergic syndrome, na nzaghachi na usoro nke 5-hydroxytryptamine-1A (5-HT1A) receptor agonist 8-hydroxy-2-di-n-propylamino-tetralin ( 8-OH-DPAT), dị ala karịa ndị na-ebubata akara a. A nwalere nsonaazụ nke nchịkwa naltrexone ka ụmụ anụmanụ nweburu agụụ mmekọahụ (ya bụ, 24 h mgbe usoro agụụ mmekọahụ) na mmeghachi omume abụọ ahụ.
Results showed that endogenous opioids mediate the establishment and maintenance of the long-lasting sexual behavior inhibition but not the drug hypersensitivity (to 8-OH-DPAT) characteristic of sexually exhausted male rats. It is concluded that although both phenomena appear as a consequence of copulation to satiation and follow a same time course of recovery, they A na-emepụta usoro dị iche iche.
PsycINFO Database Record (c) 2013 APA, all rights reserved.
;