Pharmacol ante. Iul 2018 27: 9: 821. doi: 10.3389 / fphar.2018.00821.
Price AE1, Anastasii NC1,2, S. Stutz1, JD Hommel1,2, A. Cunningham1,2.
Abstract
Bulimia inordinatio (lecto) praemium distinctum dysfunctional Hedonic actis processus cibum attractio. Activation de serotonin (5 HT-) 5 HT-2C (Felis 5 HT-2CR) attractio cibo reprimit et sic praeparat praemium actis mores conformare lectus. Hoc studio HT-aestimatione ab effectis 52CR activation via HT-electionem selectivam 52CR agonist WAY163909 in manducans binge-related behaviors in adulta masculum Sprague-Dawley mures inclusi essent. WAY163909 low doses (1.0, 2.0 mg / kg) oppressus est summus adipem cibum (HFF) binge attractio, sed non binge non-vexillum cibum attractio. WAY163909 (1.0 mg / kg) et attenuatus operant respondendi auto-certis terminis administratum HFF pellets Boiron cedulas et progressivos ordines Ratio autem habeo, significans 5 HT-2CR activation and motivational proprietatibus HFF suppressa ea potius confirmat, respectively. Hi Inventiones suadeant ut HT-activation de 52CR sit effective ad reprimendam in patientibus manducans binge NOBIS PACEM via De proprietatibus earumque oppres potius confirmat et motivational HFF. Hoc opus futurum sustinet studiis HT-targeting est 52CR curatio in lecto.
Keywords:
5 HT2C-receptor; binge manducans; princeps adipem cibum causam; serotonin
PMID: 30100875
PMCID: PMC6072841
DOI: 10.3389 / fphar.2018.00821
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