Kunenepa kwambiri (Silver Spring). 2020 Mar;28(3):601-608. doi: 10.1002/oby.22731.
Ding Y1, Ji G2, Li G1, Zhang W1, Hu Y1, Liu L1, Wang Y1, Hu C1, von Deneen KM1, Han Y3, Cui G.3, Wang H4, Wires CE5, Manza P5, Tomasi D5, Volkow ND5, Nie Y2, Wang GJ5, Zhang Y1.
Kudalirika
KUCHITA:
Cholinga cha phunziroli chinali kufufuzira kusintha kosinthika kwa magwiridwe antchito (FC) mkati ndi kulumikizana pakati pa maukonde opumulira aboma omwe akukhudzidwa ndi malovu, olamulira akuluakulu, komanso kulowererapo kwa omwe ali ndi kunenepa kwambiri (OB).
ZITSANZO:
Pogwiritsa ntchito kulingalira kwa magwiridwe antchito maginito opanga maginito ndi kusanthula kodziyimira pawokha ndi FC, zosintha mkati ndi kulumikizana pakati pamaukonde aboma mu 35 OB ndi 35 control-weight control (NW) zidafufuzidwa.
ZOKHUDZA:
Poyerekeza ndi NW, OB idawonetsa kuchepa kwa mphamvu ya FC mu cortex ya ventromedial pre mbeleal cortex ndi posterior cingate cortex / precuneus mkati mwa intaneti ya mode-default, dorsal anterior cingate cortex mkati mwa sekunde network ya Sence (SN), bilateral dorsolateral prefrontal cortex-angular gyrus mkati mwa network yakutsogolo. (FPN), ndikuwonjezera mphamvu ya FC mu insula (INS) (Pcholakwika chabanja <0.0125). Mphamvu zakuthambo zakunja kwa cingate cortex FC zinali zolumikizana molakwika ndi kulakalaka chakudya, kumanzere kwa dorsolateral preortal cortex FC mphamvu idalumikizidwa molakwika ndi kuchuluka kwa Yale Food Addiction Scale, ndipo mphamvu ya INS FC yolondola idalumikizidwa bwino ndikulakalaka chakudya chambiri chambiri. Poyerekeza ndi NW, OB idawonetsanso kuchuluka kwa FC pakati pa SN ndi FPN yoyendetsedwa ndi FC yosinthidwa yamayiko awiri INR ndi anterior cingate cortex-angular gyrus.
MAFUNSO:
Kusinthana ku FC mkati ndi zochitika pakati pa SN, network-mode network, ndi FPN zitha kupangitsa kuti chakudya chikulimbikitse kwambiri (kulakalaka), kusayang'anira kudya moperewera (kuchuluka kwakukakamiza), ndikuwonjezera chidziwitso cha njala (kulowererapo) OB.
PMID: 32090510
DOI: 10.1002 / oby.22731