Eur Neuropsychopharmacol. 2018 Sep 19. pii: S0924-977X (18) 30818-6. doi: 10.1016 / j.euroneuro.2018.09.006.
Fujino J1, Kawada R2, Tsurumi K2, Takeuchi H2, Murao T2, Khalimon A2, Tei S3, Murai T2, Takahashi H4.
Kudalirika
Zowonongera zomwe zidawoneka ndizotheka kupitiliza ndalama, kapena kuchitapo kanthu, ngakhale zili ndi ndalama zambiri mtsogolo kuposa mapindu, ngati ndalama za nthawi, ndalama, kapena khama zidachitidwa kale. Zosankha zamtunduwu ndizofala kwambiri m'moyo weniweni ndipo zaphunziridwa m'mabuku osiyanasiyana. Kafukufuku wam'mbuyomu ndikuwunika kwachipatala akuwonetsa kuti kupanga zisankho pamtengo wokwera mtengo kumasinthidwa mu vuto la njuga (GD). Komabe, njira zamomwe timagwiritsira ntchito popanga chisankho pansi pa mtengo wonyika mu GD sizikudziwika konse, momwemonso ubale wawo ndi zovuta zam'gulu lodwalali. Apa, pophatikiza magwiridwe antchito amatsenga komanso ntchito yomwe idawonetsa chitsanzo chowoneka bwino cha mtengo wowotchera, tidafufuza maulalo a neural panthawi yopanga chisankho pamtengo wokwera mu GD. Sitinapeze kusiyana kwakukulu mu mphamvu yotsika mtengo yamphamvu pakati pa GD ndi magulu owongolera athanzi (HC). Komabe, mphamvu yakuwotchera mtengo kwa odwala omwe ali ndi GD idawonetsa kuphatikiza kwakanthawi kodziletsa komanso nthawi yayitali ya matenda. Tinapezanso kuchepetsedwa kwa neural activation mu dorsal medial pre mbeleal cortex panthawi yopanga chisankho pamitengo yotsika ya gulu la GD poyerekeza ndi gulu la HC. Kuphatikiza apo, mwa odwala omwe ali ndi GD, kuchuluka kwa maopaleshoni m'derali sikugwirizana ndi kutalika kwa matenda. Zotsatira izi zili ndi tanthauzo lachipatala. Kafukufukuyu athandizira kumvetsetsa bwino kwamachitidwe omwe asinthidwa popanga zisankho mu GD.
MAFUNSO: Kupanga zisankho; Ntchito yamagalasi yotsatsira; Kusokonezeka kwa njuga; Mial prefrontal kotekisi; Njuga zachikhalidwe; Zowononga mtengo
PMID: 30243683
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