Prog Neuropsychopharmacol Nthenda ya Psychiatry. 2019 Dec 20: 109853. doi: 10.1016 / j.pnpbp.2019.109853.
Zack M1, St George R2, Clark L3.
Kudalirika
Ngakhale pali kuwonjezeka kwachipatala kuzolowera zamakhalidwe, zomwe vuto lakutchova njuga ndilo chitsanzo, pali kumvetsetsa pang'ono pamalingaliro amikhalidwe (yosagwirizana ndi zinthu) yomwe imawathandiza kuti akhale 'osokoneza bongo' m'njira yomwe ili ofanana ndi mankhwala osokoneza bongo. Malinga ndi kugwiritsa ntchito kwamphamvu pakulimbikira kuphunzira zakumwa zoledzeretsa, zotsatira zachindunji zamankhwala kuti amasule dopamine zitha kubweretsa kukwezedwa kosalekeza kwamphamvu. Nkhaniyi ikuyang'ana kwambiri kusatsimikizika kwa mphotho, yomwe akuti ndi gawo lalikulu la kutchova juga komwe kumapangitsa kuti munthu akhale ndi vuto losokoneza bongo. Timalongosola zamphamvu za kuyankha kwa dopamine pakukayika komwe kumatha kuloleza kukula kwofanizira kolimbikitsana, komanso kufunikira kwake pakukonda zamakhalidwe. Timasanthula umboni wamasulidwe kuchokera kuzipangizo zamtsogolo zamankhwala komanso kafukufuku wamankhwala wa anthu, kuphatikiza maphunziro a anthu omwe ali ndi vuto la kutchova juga. Kuphatikiza apo, tikulongosola umboni wa 1) zoyipa zakusiyidwa kwa mphotho yomwe ikuyembekezeredwa ngati chopanikizika ndikulimbikitsa chidwi, 2) zotsatira zakusatsimikizika kwa mphotho monga chitsimikizo chamtengo wapatali, 3) kapangidwe kake ka Makina amakono a Masewera a Pakompyuta (EGMs) potengera njira izi, 4) zofananira ndi malingaliro olakwika a psychosis pakupanga ndikusunga zopotoza zokhudzana ndi kutchova juga. Mtundu wouziridwa ndi mitunduyi umatanthauzanso kuwonongeka kwa zizolowezi zina zokhazokha, komanso kupereka njira zowonjezeretsa chithandizo chamitsempha, zamankhwala ndi zamaganizidwe amisala yokhudza kutchova juga, komanso njira zochepetsera kapangidwe ka EGM.
MAFUNSO: Dopamine; Makina opanga masewera amagetsi; Kutchova njuga; Kuzindikira; Kusatsimikiza
PMID: 31870708
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