Scand J Psychol. 2011 Feb;52(1):28-34. doi: 10.1111/j.1467-9450.2010.00837.x.
Linnet J, Møller A, Peterson E, Gjedde A, Doudet D.
Center of Functionally Integrated Neuroscience, Aarhus University, Arhus University Hospital, Arhus C, Denmark. [imelo ndiotetezedwa]
Kudalirika
Dopamine system imakhudzidwa kuti ikhudze njuga pamasewera a njuga. Makamaka, kutulutsidwa kwa dopamine mu ventral striatum kumawoneka kuti kumakhudza kupanga zisankho muvuto. Kafukufukuyu adafufuza kutulutsidwa kwa dopamine mu ventral striatum pokhudzana ndikuchita njuga pa Iowa Ginja Task (IGT) mu 16 Pathological Gambler (PG) ndi 14 Healthy Controls (HC). Tidagwiritsa ntchito Positron Emission Tomography (PET) kuyeza kuthekera kosunga kwa [(11) C] raclopride kuti dopamine D2 / 3 receptors panthawi yoyambira komanso kutchova juga. Tidawerengera omwe amachepetsa mphamvu yakumanga kwa raclopride pamasewera a ventral striatum panthawi yanjuga (ndikuwonetsa kutulutsidwa kwa dopamine) ikhoza kukhala yogwirizana ndi magwiridwe apamwamba a IGT mu Healthy Controls, koma magonedwe apansi a IGT mu Pathological Gambler. Zotsatira zake zinawonetsa kuti Pathological Gambler omwe amatulutsidwa ndi dopamine mu ventral striatum anali ndi kutsika kwakukulu kwa IGT kuposa Healthy Controls. Kuphatikiza apo, kutulutsidwa kwa dopamine kumalumikizidwa ndi magwiridwe apamwamba a IGT mu Healthy Controls ndikuchepetsa kwambiri magwiridwe a IGT mu Pathological Gambler. Zotsatira zake zikuwonetsa kuti kumasulidwa kwa dopamine kumakhudzidwa popanga zisankho mosasinthasintha komanso molakwika. Izi zitha kupangitsa kuti kumvetsetsa bwino kwa kusokonekera kwa dopaminergic mu njuga zam'magazi komanso zosokoneza bongo zokhudzana ndi zinthu.
© 2010 Olembawo. Scandinavia Journal of Psychology © 2010 The Scandinavia Psychological Associations.
;