Int Gambl Stud. 2018;18(2):269-285. doi: 10.1080/14459795.2018.1469658.
Balodis IM1,2, Linnet J3,4, Arshad F2, Worhunsky PD1, Stevens MC1,5, Pearlson GD1,5,6, Potenza MN1,6,7,8.
Kudalirika
Kafukufuku wofufuza wowunikira akuwonetsa kusintha mu njira za fronto-striatal neurocircuitry mu gayambano yamagetsi (GD) panthawi yoyembekezeka kukonzekera, yomwe imatha kukhumudwitsa kupanga zisankho. Komabe, mpaka pano ndizochepa zomwe zimadziwika zokhudzana ndi chisankho cha fronto-striatal. Ndikukumana ndi neuroimaging, otenga gawo a 28 GD ndi 28 wathanzi (HC) adachita Monetary Incentive Delay Task (MIDT). Coefficients ya pearson yowunikira ntchito yapasaka ya Iowa Kutchova Juga (IGT) ndi ntchito ya neural panthawi ya chiyembekezo (A1) pokonza pa MIDT kudutsa magulu ophatikiza a GD ndi HC. Magulu a HC ndi GD sanawonetse kusiyana kwakukulu pakuchita kwa IGT, ngakhale panali mawonekedwe apamwamba a IGT mu gulu la HC pamagawo awiri omaliza a IGT. Kuphatikiza kwa ubongo wathunthu m'magulu ophatikizana a HC ndi GD kunawonetsa kuti MIDT BOLD siginecha mu ventral striatum / caudate / ventromedial prefrontal cortex ndi anterior cingulate zigawo pakuyembekeza kupambana zambiri zogwirizana ndi ziwonetsero zonse za IGT. Gulu la GD lidalinso ndi kuchuluka kwa osuta fodya, komanso kulumikizana pakati pa kuchitidwa kwa neural poyembekeza ku MIDT kumatha kugwirizana ndi gawo la njuga ndi / kapena kusuta kwa fodya. Phunziroli, zochitika za frontoatal panthawi yakuyembekeza mphotho ndi kutayika pa MIDT zinali zokhudzana ndikupanga chisankho pa IGT, ndikuwongoleredwa kophatikizidwa ndi chisankho cholakwika. Zomwe zapezedwa mu ntchitoyi ndi zapadera polumikiza zochitika zaubongo panthawi yogwira mphotho ndi ntchito yopanga zisankho kwa anthu omwe alibe kapena GD.
PMID: 31485192
PMCID: PMC6726408
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