Biol Psychiatry Cogn Neurosci Neuroimaging. 2017 Mar;2(2):188-195. doi: 10.1016/j.bpsc.2016.03.001.
Yip SW1, Morie KP2, Xu J2, Constable RT3, Malison RT4, Carroll KM2, Potenza MN5.
Kudalirika
MALANGIZO:
Kufanana pakati pamakhalidwe ndi zosokoneza bongo kumakhalapo. Komabe, kufananizira kwachindunji pakati pamavuto osokoneza bongo ndikosowa. Kudziwitsa kusokonezeka-kapadera (kapena kusowa kwake) kwa masinthidwe mkati mwazinthu zoyera pazinthu zatsopano kudzapititsa patsogolo kumvetsetsa kwa pathophysiology ya zosokoneza.
ZITSANZO:
Tidafanizira zoyera zazing'ono zazing'ono pakati pa anthu omwe ali ndi vuto la kutchova juga (GD; n = 38), vuto logwiritsa ntchito mankhwala osokoneza bongo a cocaine (CUD; n = 38) ndikuyerekeza bwino (HC; n = 38) ophunzira, monga momwe amayesera kugwiritsa ntchito maginito olemera kujambula kwa resonance (dMRI). Kupereka kuyerekezera kolondola kwa kufalikira mkati mwa zigawo zomangamanga zovuta (mwachitsanzo, timapepala ta cortico-limbic), kusanthula kunachitika pogwiritsa ntchito njira yolumikizira yophatikizira mitundu yakomweko (tbss_x). Anisotropy kuyerekezera koyambira kwa pulayimale ndi sekondale poyerekeza ndi kuyerekezera kudafanizidwa pogwiritsa ntchito ma ANOVA omwe adakonzedwa poyerekeza angapo mlengalenga pogwiritsa ntchito njira yopanda masango (pFWE <.05).
ZOKHUDZA:
Zotsatira zazikulu pagulu pamankhwala am'manzere amkati wamatumbo, corona radiata, ma radiation akuluakulu ndi obwera pambuyo, omwe akuphatikizira kuchepa kwa magawano pakati pa ochita nawo GD ndi CUD poyerekeza ndi omwe akuchita nawo HC. Palibe kusiyana pakati pa machitidwe anisotropy omwe adapezeka pakati pa GD ndi CUD.
MAFUNSO:
Uwu ndiye kafukufuku woyamba kufananizira mafakisoni amkati mwachindunji pakati pazolankhula ndi zosokoneza bongo komanso kafukufuku wamkulu kwambiri wa DMRI wa GD. Zomwe tapezazi zikuwonetsa kusintha kwazinthu zoyera zofananira pazowonjezera zomwe sizingatheke chifukwa chongotulutsa mankhwala osokoneza bongo kapena mowa motero kungakhale njira yodzetsa mavuto osokoneza bongo.
MAFUNSO: vuto lakumwa mowa; chizolowezi chamakhalidwe; mayendedwe onyenga (DTI); kusakhazikika; njuga zamatenda; matenda osokoneza bongo
PMID: 28367515
PMCID: PMC5373810
DOI: 10.1016 / j.bpsc.2016.03.001
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