Neuropsychopharmacology 17 Meyi 2017;
onetsani: 10.1038 / npp.2017.78
Mateusz Gola1,2, Małgorzata Mawu2, Guillaume Sescousse3, Michał Lew-Starowicz4, Bartosz Kossowski5, Marek Wypych5, Scott Makeig1, Marc N Potenza6,7,8 ndi Artur Marchewka5
Msonkhano: Dr M Gola, Swartz Center ya Computational Neuroscience, Institute for Neural Computations, University of California San Diego, 9500 Gilman Drive, San Diego, CA 92093-0559, USA, Tel: 858 500 2554 / 858 822 7543, Imeli : [imelo ndiotetezedwa]
Chithunzithunzi chovomerezeka pa 14 April 2017; Pitani patsogolo pa intaneti 17 Meyi 2017
Kudalirika
Kuonera zolaula kumafala kwambiri, makamaka pakati pa amuna achikulire. Kwa anthu ena, zolaula zimagwiritsa ntchito (PPU) ndi chifukwa chofuna chithandizo. Ngakhale kuti zolaula zili ponseponse, PPU imawunikiridwa pansi, kuphatikizapo njira zowonongeka. Pogwiritsa ntchito kujambula kwa magnetic resonance (fMRI), tinayang'ana mayankho omwe amachititsa kuti anthu asamangokhalira kuchita zinthu zolimbitsa thupi, kusokoneza malingaliro okhudzana ndi mphotho pakati pa amuna ndi akazi omwe amatha kupeza chithandizo kwa PPU ndi 28 amuna okhaokha popanda PPU. Ophunzira omwe amachititsa chidwi kuchepetsa ntchito pazithunzithunzi, momwe adalandira mphoto zolimbitsa thupi kapena zamtengo wapatali zotsatiridwa ndi ndondomeko zowonongeka. Maganizo okhudzana ndi mpweya wa okosijeni-okhudzana ndi zokhudzana ndi zovuta komanso zachuma adafufuzidwa ndikuwunika pazomwe zadzidzidzi zokhudzana ndi kugonana zomwe zinasonkhanitsidwa pa miyezi yambiri ya 24. Amuna omwe ali ndi PPU amasiyana ndi machitidwe awo okhudzana ndi zolaula koma osati m'maganizo awo ndi zithunzi zolaula. Maphunziro a PPU poyerekeza ndi maulamuliro awonetseratu kuwonjezeredwa kwa ventral striatum mwachindunji kuti adziwe zithunzi zowonongeka koma osati zokhudzana ndi kupindula kwa ndalama. Zosamvetsetseka zokhudzana ndi kufotokozera zithunzi zolaula vs Kupindula kwa ndalama kunkagwirizana kwambiri ndi kuwonjezereka kwa makhalidwe ofuna kuona zithunzi zolaula (kuganiza kuti "kufunafuna" kwakukulu), kuopsa kwa PPU, kuchuluka kwa zolaula zomwe zimagwiritsidwa ntchito pa sabata, ndi chiwerengero cha maliseche. Zomwe tapeza zimasonyeza kuti, zofanana ndi zomwe zimawonedwa ndi kutchova njuga, njira zachithunzithunzi ndi khalidwe lachikhalidwe zogwirizana ndi kuyembekezera kugwiritsira ntchito malingaliro okhudzana ndi zochitika zokhudzana ndi zochitika zokhudzana ndi zokhudzana ndi zochitika zokhudzana ndi zofunikira zogwirizana ndi PPU. Zomwe zapezazi zikusonyeza kuti PPU ikhoza kuwonetsa khalidwe lachizolowezi komanso kuti njira zothandizira kuwongolera khalidwe ndi zakumwa zoledzeretsa ziyenera kulingalira za kusintha ndi kugwiritsa ntchito kuthandiza amuna omwe ali ndi PPU.
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