AJNR Am J Neuroradiol . 2020 Jul 2. doi: 10.3174/ajnr.A6632.
HS Seo 1 , EK Jeong 2 , S Choi 3 , Y Kwon 3 , HJ Paka 4 , O Kim 5
PMID: 32616578
FAIA: 10.3174/ajnr.A6632
lē faʻatino
Faʻamatalaga ma le faʻamoemoega: O suiga o le Neurotransmitter i tupulaga talavou ua fai ma vaisu i luga o le Initaneti ma le telefoni na faʻatusatusa i faʻatonuga masani ma i mataupu pe a maeʻa togafitiga faʻamalosi. E le gata i lea, na suʻesuʻeina le fesoʻotaʻiga i le va o neurotransmitters ma aʻafiaga.
Mea ma metotia: E sefuluiva tupulaga talavou o loʻo i ai le Initaneti ma vaisu telefoni ma le 19 faʻafeusuaiga-ma le matua-matutua faʻataʻitaʻiga maloloina (tama / fafine, 9: 10; o tausaga, 15.47 ± 3.06 tausaga) na aofia ai. E sefululua tupulaga talavou ma vaisu i luga ole Initaneti ma telefoni (tama / fafine, 8: 4; tausaga, 14.99 ± 1.95 tausaga) na auai i le 9 vaiaso o togafitiga o le mafaufau. Meshcher-Garwood point-resolved spectroscopy na faʻaaogaina e fua ai le γ-aminobutyric acid ma le Glx maualuga i le pito i luma o le cingulate cortex. O le γ-aminobutyric acid ma le Glx maualuga i le vaega ua fai ma vaisu na faʻatusatusa i latou o loʻo pulea ma pe a maeʻa togafitiga faʻapitoa. Ole maualuga ole γ-aminobutyric ma le Glx e fesoʻotaʻi ma fua faʻapitoa ole Initaneti ma vaisu telefoni, faʻalavelave, atuatuvale, popole, le mautonu, ma le lelei o le moe.
Tali: Brain parenchymal ma le grey matter volume-adjusted γ-aminobutyric acid-to-creatine ratios sa maualuga atu i mataupu ma vaisu Initaneti ma telefoni (P = .028 ma le .016). Ina ua maeʻa togafitiga, o le faiʻai parenchymal-ma le grey matter volume-adjusted γ-aminobutyric acid-to-creatine ratios na faʻaititia (P = .034 ma le .026). Ole maualuga ole Glx e le'i taua tele ile mataupu ile Initaneti ma vaisu telefoni fa'atusatusa ile fa'atonuga ma le tulaga posttherapy. Brain parenchymal- ma le grey matter volume-adjusted γ-aminobutyric acid-to-creatine ratios faʻatasi ma fua faʻataʻitaʻi o vaisu Initaneti ma telefoni, atuatuvalega, ma le popole. O le Glx/Cr e le lelei le feso'ota'iga ma fua le moe ma fua lelei o le moe.
Faaiuga: Ole maualuga ole γ-aminobutyric acid ma le faʻalavelaveina o le paleni ole γ-aminobutyric acid-to-Glx e aofia ai le glutamate i le pito i luma o le cingulate cortex e mafai ona fesoasoani i le malamalama i le pathophysiology ma togafitiga o vaisu Initaneti ma telefoni ma faʻalavelave faʻapitoa.
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