Faallooyinka: Daraasad dhowaan la sameeyay oo xaqiijineysa in receptor androgen receptor uu hoos udhacayo jiirka oo kacsan. Daraasadu waxay ogaatay in dadka qaata soo laabashada ay caadi ku soo noqonayaan saacadaha 72, laakiin awooda galmada oo buuxda waxay qaadataa 15 maalmood inay si buuxda u soo laabtaan. Waxyaabaha kale waa inay ku lug lahaadaan xannibaadda galmada ee dhaqanka galmada ee maalmaha 15
Romano-Torres M, Phillips-Farfán BV, Chavira R, Rodríguez-Manzo G, Fernández-Guasti A.
Neuroendocrinology. 2007; 85 (1): 16-26. Epub 2007 Jan 8.
Waaxda Dhakhtarka Pharmacobiology, Centro de Investigación Estudios Avanzados, Mexico City, Mexico.
aan la taaban karin
Dhawaan waxaan soo bandhignay in 24 h kadib copulation to satiety, waxaa hoos u dhacay cufnaanta androgen receptor density (ARd) aagga aaladda preoptic (MPOA) iyo aaladda ventromedial hypothalamic nucleus (VMH), laakiin kuma jiraan sariirka xudunta u ah stria teralis (BST).
Daraasaddan ayaa loo qorsheeyay in lagu falanqeeyo haddii ARD wax ka bedesho meelahaas iyo meelaha kale ee maskaxda, sida amygdala medial (MeA) iyo septum lateral, qaybta qaybta qaybta (VS), waxay la xidhiidheen isbeddel ku dhaca dabeecada galmada ka dib galmada galmada.
Ragga ragga ah ayaa loo sadqeeyey 48 h, 72 h ama 7 maalmood kadib satiety galmada (4 h ad libitum copulation) si loo go'aamiyo ARd by immunocytochemistry; Intaa waxaa sii dheer, heerarka sertosterone serum-ka waxaa lagu cabiray kooxo madax-bannaan oo lagu goglay isla waqtiyadaas. Tijaabo kale, ragga waxaa lagu tijaabiyay soo kabashada dabeecada galmada 48 h, 72 h ama 7 maalmood ka dib satiety galmada. Natiijooyinku waxay muujiyeen in 48 h ka dib satiety 30% labka ay soo bandhigeen hal il bax iyo inta hartay ee 70% waxay muujiyeen xannibaad dhameystiran oo ku saabsan dhaqanka galmada..
Hoos udhaca habdhaqanka galmada waxaa weheliya hoos u dhac ku yimid barnaamijka 'ARd' oo si gaar ah uga socda qaybta MPOA-medial (MPOM). Labaatan iyo laba saacadood ka dib satiety galmada waxaa dib u soo kabashada nashaad galmo ay weheliso koror ku yimid ARd si loo xakameeyo heerarka MPOM iyo culeyska xad dhaafka ah ee ARd ee LSV, BST, VMH iyo MeA.
Heerarka testosterone-ga ee loo yaqaan 'Serum testosterone' waa kuwo aan la isku habeynin muddada lagu jiro ka dib-satiety-ga. Natiijooyinka waxaa looga wada hadlayaa iyada oo lagu saleynayo waxyaabaha u dhigma iyo farqiga u dhexeeya ARd ee qaybaha maskaxda ee gaarka ah iyo dhaqanka galmada.
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