J Neurosci. 2002 Jun 1; 22 (11): RC225. Epub 2002 May 23.
Roitman MF1, Na E, Anderson G, Jones TA, Bernstein IL.
inahaneloang
Sensitization ea lithethefatsi, joalo ka amphetamine, e amahanngoa le liphetoho morphology ea li-neurons ho li-nucleus accumbens, e leng sebaka sa boko se bohlokoa ho susumetsa le ho fumana moputso. Lithuto tse tlalehiloeng mona li bonts'a hore motataisi ea matla oa tlhaho, ho fokotseha ha sodium le takatso ea letsoai e amanang le eona, e lebisa phetohong ea li-neurons ka li-nucleus accumbens. Li-neuron tsa mahareng tsa "spiny" "khetla ea" likhoto "tse nang le lits'oants'o tsa sodium li ne li na le makala a dendritic haholo ho feta taolo. Ntle le moo, ho fumanoe nalane ea ho theoha ha sodium ho ba le litlamorao tsa maikutlo, e lebisang ho likarabo tse ntlafalitsoeng tsa psychostimulant ho amphetamine. Ka hona, liphetoho tse amanang le neuronal tse tloaelehileng letsoai le tšebeliso ea lithethefatsi li ka fana ka mokhoa o akaretsang oa likarabo tsa boitšoaro tse ntlafalitsoeng ho hlahisoa ka katleho ho mathata ana.
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