Tšebeliso ea dopamine e entsoeng ke lithethefatsi e ka baka boitšoaro bo bobe ba ho kopanela likobo. Na see se na le taba ho ba tloaetseng ho thethefatsa dopamine ka tšebeliso e boima ea litšoantšo tsa bootsoa?
Parkinson ea Sehlahisoa ea Parkinsonism. 2011 May;17(4):260-4. doi: 10.1016/j.parkreldis.2011.01.009.
Hassan A, Bower JH, Kumar N, Matsumoto JY, Fealey RD, Josephs KA, Ahlskog JE. Parkinson ea Sehlahisoa ea Parkinsonism. 2011 Feb 8; Lefapha la Neurology, Clinic ea Mayo, Rochester, MN 55905, USA.
TLHOKOMELISO: Boitšoaro bo qobelloang bo susumetsoang ke li-dopamine agonists hangata ha bo fihlellehe letotong la bongaka, haholoholo haeba ho sa botsoe ka ho khetheha ka.
Sepheo: Ho tseba makhetlo a boitšoaro bo qobelloang tleliniking ea Parkinson's (PD) moo bakuli ba tšoaroang ke agonist ba neng ba lula ba botsoa ka boits'oaro bo joalo.
Mekhoa: Re sebelisitse database ea Mayo Health Science Research ho netefatsa bakuli bohle ba PD ba nkang dopamine agonist ka nako ea lilemo tse peli (2007-2009). Bohle ba ile ba bonoa ke setsebi sa basebetsi ba Mayo-Rochester Movement Disways Staff ba neng ba lula ba botsa ka khatello ea boitšoaro.
LITLHAKISO: Ho bakuli ba 321 PD ba nkang agonist, 69 (22%) ba bile le boits'oaro bo khothalletsang, 'me 50 / 321 (16%) e ne e le pathologic. Leha ho le joalo, ha tlhahlobo e ne e lumelletsoe ho bakuli ba nkang litekanyetso tsa agonist tse neng li sa phekolehe ho feta tekano, boits'oaro ba methapo ea kutlo bo tlalehiloe ka 24%. Li-subtypes e ne e le: papali ea chelete (25; 36%), hypersexuality (24; 35%) ts'ebeliso ea likhomphutha (18; 26%). Boholo ba linyeoe tse amehileng (12%) li ne li nka carbidopa / levodopa ka nako e tšoanang. Har'a ba nang le ho latela ho lekaneng, boits'oaro bo botle bo rarollotsoe ka botlalo kapa karolo e itseng ha tekanyetso ea dopamine agonist e fokotsoa kapa e fela.
TLHOKOMELISO: Phekolo ea dopamine agonist ea PD e na le kotsi e kholo ea boits'oaro ba pathological. Sena se etsahetse ho 16% ea bakuli ba tšoaroang ke agonist; leha ho le joalo, ha ho hlahlojoa bakuli bao tekanyetso ea bona e neng e le bonyane ka tekanyo ea kalafo, khafetsa e ile ea tlolela ho 24%. Ho becha ka tsela ea tlhaho le khatello ea maikutlo li ne li atile haholo. Kalafo ea Carbidopa / levodopa e nkuoeng ka nako e le 'ngoe le dopamine agonist e ile ea bonahala e le karolo ea bohlokoa ea kotsi.
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