E se eka 11, 2015
Dopamine ke len messengerosa la lik'hemik'hale bokong bo amanang haholo le thabo le moputso. Tsoelo-pele ea morao-rao ea mahlale joale e fana ka leseli mabapi le likarolo tse nepahetseng tsa dopamine ts'ebetsong ea moputso.
Pampiri e ncha e phatlalalitsoeng makasineng ea hona joale ea Likokoana-hloko tsa likokoana-hloko e kenyelletsa dopamine ho bokhoni ba motho ba ho susumetsoa ke meputso e liehang.
Batho ba rata ho matlafatsoa hanghang mme ba rata ho fumana meputso e liehang haholo ka nako. Ka lebaka leo, hangata batho ba khetha khetho e nyane hang hang ha ba fuoa khetho e kholo.
Ts'ebetso ena ea ho etsa liqeto ea ho bekha melemo ho latela litšenyehelo tsa sephetho se itseng e bitsoa "theolelo ea ho lieha". Le ha re etsa lihlahlobo tsena tsa litjeo ka mokhoa o bonahalang o se thata, borasaense ba ntse ba ithuta ka moo boko bo etsang lits'ebetso tsena tse rarahaneng.
Phuputsong ea morao tjena, bafuputsi Univesithing ea North Carolina ho Chapel Hill le Stanford Univesithi ba sebelisitse mehlala ea methapo ho lekola karolo ea neurotransmitter ena ho latela ka hloko likarolo tse ikhethileng tsa liqeto tse thehiloeng ho boleng.
Taba ea mantlha, ba ile ba koetlisa likhoto hore li khethe pakeng tsa likhetho tse peli tse fapaneng, moputso o monyane o monate o neng o ka jeoa hanghang, kapa moputso o moholo o monate o ileng oa tlisoa feela kamora ho lieha ho fapana.
Sengoli se phahameng Dr. Regina Carelli o hlalositse seo ba se fumaneng, "Re fumane hore dopamine e tšoaea khetho e ratoang haholo; dopamine e eketsehileng e ile ea bonoa bakeng sa matšoao a bontšang meputso e meholo kapele, empa sena se ile sa fokotseha ha tieho ea moputso o moholo e ntse e eketseha. ” Phetoho ena ea ho lokolloa ha dopamine le tloaelo e amanang le eona ea ho khetha meputso e menyenyane ea kapele ho feta meputso e meholo e liehang e tsamaellana le ts'ebetso ea ho fokotsa litheko.
Ka mor'a moo, ba sebelisa mokhoa o tsejoang e le optogenetics ka karolo ea bobeli ea likhoto, ba ile ba laola hantle mosebetsi oa dopamine neurons nakong ea matšoao a neng a bontša moputso o moholo kapa o liehang. Teko ena e senotse hore, ka ho 'bapala morao' mekhoa ea dopamine ho lokolloa e hlokometsoeng lethathamong la pele la likhoto (ha ba ntse ba nahanisisa ka khetho eo ba lokelang ho e etsa), bafuputsi ba ne ba ka ba leqe ho etsa liqeto tse fapaneng nakong e tlang.
"Liphuputso tsena tse ncha tse khahlisang li fana ka maikutlo a hore dopamine e bapala karolo e rarahaneng ho thusa ho tataisa likarolo tse ikhethileng tsa boits'oaro ba ho etsa liqeto," ho boletse Carelli.
Dr. John Krystal, Mohlophisi oa Likokoana-hloko tsa likokoana-hloko, a re, “Ho fokotsa litheolelo ke ts'ebetso ea bohlokoa le e sa utloisisoeng hantle. Ho utloisisa hore na e sebetsa joang ho hlakisa hore na joang dopamine e fana ka moputso bokong. E ka thusa hape ho theha maano a thibelo ea ts'ebeliso e mpe ea lithethefatsi, mathata a papali ea chelete, le maemo a mang a bongaka moo litheolelo li ka bang le seabo.
Hlahloba ho eketsehileng: Matšoao a lik'hemik'hale bokong a thusa ho tataisa liqeto tse kotsi
Boitsebiso bo eketsehileng: Sengoloa ke "Mesolimbic Dopamine Dynamically Tracks, 'me e hokahantsoe le mabaka a hlakileng a liqeto tse thehiloeng boleng" ke Michael P. Saddoris, Jonathan A. Sugam, Garret D. Stuber, Ilana B. Witten, Karl Deisseroth, le Regina Monghali Carelli (DOI: 10.1016 / j.biopsych.2014.10.024). Sengoloa se hlaha ka Likokoana-hloko tsa likokoana-hloko, Moqolo 77, Issue 10 (Mots'eanong oa 15, 2015)
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