By Marijke Vroomen Durning, RN | June 12, 2012
Ho nahana ka PET ho bontšitse khokahano lipakeng tsa tse tlase dopamine maemo le mabifi ho batho ba baholo ba phetseng hantle - litlamorao tse makatsang ho fapana le tse neng li entsoe pele, ho boletse bafuputsi inehelano ea Seboka sa Selemo le Selemo sa Mekhatlo ea Bongaka ba Nyutlelie, Miami Beach, Fla., bekeng ena.
The neurobiology ea mabifi ha e utloisisoe hantle, empa bafuputsi ba hlokometse hore ho na le kamano pakeng tsa serotonin, neurotransmitter, le boits'oaro bo itseng bo mabifi. Ho etsa patlisiso ena ho ea pele, bafuputsi ba tsoang Univesithing ea RWTH Aachen e Aachen, Jeremane, ba ile ba hlahloba 18 hea batho ba baholo ba holima li-20 tsa bona bakeng sa mabifi ba sebelisa mosebetsi oa boits'oaro ba kelello o tsejoang ka hore ke lintlha tsa tšusumetso ea khatello ea kelello. Ba ne ba batla ho bona hore na maemo a holimo a dopamine, a amehang boithabisong le moputsong, a eketsa mabifi, empa liphetho ha li joalo ka theorate.
(HAPE: PET Tracer e Bontša Li-Brains tse Sebetsang Li na le Beta-Amyloid e Nyane)
Ka ho bapala papali ea komporo, moo barupeluoa ba ileng ba bolelloa hore mohanyetsi ka phapusing e ngoe o tla khona ho qhekella le ho utsoa tse ling tsa lintlha tsa bankakarolo, lithuto li ka khalemela motho ea qhekellang (ea neng a le sieo ka nnete), ho itšireletsa khahlanong le Mohanyetsi ka ho tobetsa konopo ea ho itšireletsa khafetsa, kapa u tsoelepele ho bapala papali ho ntlafatsa bokhoni ba bona ba ho hapa chelete. Sena se ne se bontša ho tiea.
Lithuto li ile tsa hlahlojoa ke PET ka F-18 FDOPA, biomarker e bonesang bokhoni ba li-enzyme tsa ho kopanya serotonin. ThHo ile ha sekasekoa lintlha tse latelang ho lekanya kamano pakeng tsa bokhoni ba tlhatlhobo ba dopamine le boitšoaro bo mabifi.
Bafuputsi ba fumane hore ho na le tšusumetso e kholo ho karabelo e mabifi libakeng tsa bokong moo dopamine synthesis e neng e le teng, haholoholo ho basal ganglia, eo har'a mesebetsi e meng e kenyelletsang setsi sa khothatso. Miho hlaseloa ka matla ke ho amahanngoa le maemo a phahameng a dopamine kahare ho bohareng ba 'mele le ho striatum, e phethang karolo ea ho hlophisa le ho etsa lipatlisiso..
ShebanaRona ka karolo ea moputso oa chelete oa PSAP e ile ea bonoa har'a lithuto tse nang le bokhoni bo bongata ba tšebetso ea dopamine, athe ba nang le bokhoni bo tlase ba ne ba le kotsing ea ho sebetsa ka mokhoa o hlekefetsang, ka boits'ireletso, kapa ka bobeli, bafuputsi ba boletse..
Sengoli se etellang pele Ingo Vernaleken, MD o itse: "Re nahana hore mokhoa o sebetsang hantle oa moputso o etsa hore motho a tsitlelle ho phephetso." "Leha ho le joalo, re ke ke ra khetha hore maemong ao taba e ka ruang ka kotlolloho ho motho ea mabifi, ntle le mekhoa e meng, tlhabollo e ka ba ka tsela e 'ngoe e fapaneng."
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