Neurosci Biobehav Rev. 2003 Nov;27(7):671-82.
mohloli o moholo
Lefapha la Biology ea Batho, Setsi sa Saense ea Bophelo, Univesithi ea Cape Town, Observatory 7925, Afrika Boroa. [imeile e sirelelitsoe]
inahaneloang
RUSSELL, VA Dopamine hypofunction e kanna ea hlahisoa ke bofokoli bo hlahisoang ke bosholu ba dopamine ka khubung ea leqhubu la mofuta oa rat bakeng sa tlhokomelo ea bofokoli ba khatello ea kelello-lenonyeletso la boithati. NEUROSCI. BIOBEHAV. REV.27 (2003). Ts'oenyeho ho glutamate, dopamine le norepinephrine sebetsa bokong ba mofuta oa phoofolo ea lefutso bakeng sa tlhokomeliso ea khatello ea methapo ea kelello (ADHD), litheko tse ikhethileng tsa hypertensive rat (SHR), le tlhaiso-leseling e fumanoeng ho bakuli ba nang le ADHD e hlokahala bakeng sa ho ithuta le tataiso ea tataiso e tataisoang le moputso. Bopaki bo nkiloeng ho (i). neuropharmacology ea lithethefatsi e sebetsang ho phekola matšoao a ADHD, (ii). lithuto tsa liphatsa tsa lefutso le neuroimaging tsa bakuli ba ADHD, hammoho le (iii). boits'oaro le biochemistry ea mehlala ea liphoofolo, e fana ka maikutlo a ho hloleha ha dopamine neurons. SHR e fokotse ts'usumetso ea ts'usumetso ea dopamine le pherekano molaong oa ho lokolloa ha norepinephrine le lits'ebetso tsa bobeli tsa man messengerosa a senyehileng, cAMP le calcium. Ntle le moo, bopaki bo ts'ehetsa bofokoli bo ikhethileng kholonth ea bokono ea SHR e ka kenyang matlafatso ea boitšoaro bo nepahetseng.
;