Berry, Anne, UC Berkeley
Berry, Anne, UC Berkeley, https://orcid.org/0000-0002-5086-3643
[imeile e sirelelitsoe], [imeile e sirelelitsoe]
Letsatsi la phatlalatso: Loetse 5, 2018
Mohatisi: UC Berkeley
https://doi.org/10.6078/D1JM3K
Tlhaloso
Berry, Anne; Berry, Anne (2018), methapo ea Dopaminergic e tlisang phetoho e tloaelehileng molemong oa ho tšoenyeha ka tšebeliso: tlatsetso, UC Berkeley Dash, Dataset, https://doi.org/10.6078/D1JM3K
inahaneloang
Ho tšoenyeha ka sepheo sa ts'ebetso ho amahantsoe le ts'ebetso e fetotsoeng kahare ho litsela tsa corticolimbic tse hokahanyang amygdala le rostral anterior cingrate cortex (rACC), e fumanang ho kenella ka bongata ho dopaminergic. Leha setso se tummeng se sebelisa lentsoe "ho hloka botsitso" ha lik'hemik'hale "ho hlalosa pathophysiology ea maemo a kelello joalo ka mathata a ho tšoenyeha, re tseba hanyane ka moo phapang ea dopamine neurochemistry e amanang teng le phapang ea matšoenyeho le tšebetso tse lipakeng tsa potoloho ea corticolimbic. Re rarolle bothata bona ka ho hlahloba ho fapana hoa batho ba bang ho lokolloeng ha dopamine phomolong re sebelisa [11C] raclopride PET, khokahano e sebetsang pakeng tsa amygdala le racC e sebelisang fMRI ea ho phomola, le mekhoa ea ho tšoenyeha ho batho ba baholo ba phetseng hantle. Re fumane kamano e mpe lipakeng tsa ho lokolloa ha dopamine le tšabo ea mofuta o joalo hore batho ba nang le dopamine e phahameng ba lokolloe amygdala le rACC e itlalehileng e na le ts'oaetso. Ho tšoenyeha ka litšobotsi tse tlase ho ne ho boetse ho amahanngoa le khokahano e sebetsang ea RACC-amygdala basement. Ho kenyelletsa moo, khokahano e sebetsang e bonts'itse likamano tse mpe tse mpe le tokollo ea dopamine hoo batho ba nang le tumellano ea tšebetso ea RACC e fokotsehileng ba bonts'itseng maemo a holimo a tokollo ea dopamine libakeng tsena. Ka kopanelo, liphumano tsena li kenya letsoho mefuteng ea hypodopaminergic ea matšoenyeho le ho ts'ehetsa ts'ebeliso ea ho kopanya mehato ea fMRI le PET ea ts'ebetso ea methapo ea kutlo ho ntšetsa pele kutloisiso ea rona ea lits'ebetso tsa mantlha tse amanang le batho.
mekhoa
Ho fanoa ka lisebelisoa tse tlatsetsang mona, tse kenyelletsang tlhahlobo ea ho lokolloa ha dopamine ho striatum le likamano le matšoenyeho a mokhoa. Ho kenyelletsa moo, re kenyelletsa tlhahlobo ea ho lokoloha ka letsohong le letšehali la hemisphere dopamine le khokahano ea funcitonal bakeng sa cortex ea amygdala le rostral anterior cingrate cortex.
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