Na Matšoenyeho a Matšoenyeho Ahle a Kelello?
ScienceDaily (Mots'eanong oa 12, 2008) - Ba sebelisa single-Photon emission composed tomography (SPECT), bafuputsi ba The Netherlands ba ile ba khona ho bona phapang e teng ka har'a likelello tsa batho ba nang le mathata a ho tšoenyeha ka kakaretso a sechaba (hape a tsejoa e le phobia ea sechaba), ba fana ka bopaki ba lebaka la tlhaho le belaelloang la tlhaho ho se sebetse hantle.
Boithuto bona bo bapisitse methapo ea methapo ea serotonin le dopamine neurotransmitter bokong ba batho ba 12 ba fumanoeng ba e-na le bothata ba ho tšoenyeha ka sechaba, empa ba sa kang ba sebelisa meriana ho e phekola. le sehlopha sa taolo ea batho ba phetseng hantle ba 12 ba neng ba ts'oaroa ke thobalano le lilemo.
Lihlopha tsena ka bobeli li ile tsa entoa ka motsoako o nang le mahlaseli a kotsi o tlamang le likarolo tsa sistone ea boko le ea dopamine. Hang ha e sebelisoa, radiotracer e senotse liphetoho tse sebetsang lits'ebetsong tsena ka ho metha tlamo ea radioactive ho thalamus, midbrain le lipon (tse tsejoang hore li sebetsoa ke serotonin) le ho striatum (e tsejoang e sebetsoa ke dopamine). Mosebetsi o fetotsoeng oa ho nka libaka tsena o bontšitse boemo bo boholo ba ts'ebetso e senyehileng.
"Boithuto ba rona bo fana ka bopaki bo tobileng ba ho nka karolo ha sistimi ea dopaminergic bokong ba khatello ea maikutlo ho bakuli ba neng ba sena monyetla oa ho fuoa meriana pele., ”Ho boletse Dr. van der Wee, MD, Ph.D., lefapheng la tsa mafu a kelello le Leiden Institute for Brain and Cognition Setsing sa Bongaka sa Leiden University, Leiden (le pejana Setsing sa Rudolf Magnus sa Neuroscience, University Medical Setsi Utrecht, Netherlands). "Ho bontša hore matšoenyeho a sechaba a na le karolo ea 'mele le boko."
Serotonin le dopamine (li-neurotransmitters, kapa lintho tse ikarabellang ka ho fetisa lipontšo ho tloha mothong o mong ho ea ho o mong) li sebetsa ho li-receptors bokong. Haeba methapo ea kutlo e felile, melaetsa e ke ke ea kena bokong hantle. Sena se ka fetola tsela eo boko bo aranang ka eona maemong a tloaelehileng a bophelo, e lebisang ho tšoenyehong.
Liphuputso tse ling tsa neuroimaging li bonts'itse ho sa tloaelehang hoa ts'ebeliso ea tsoekere le oksijene bokong, ho latela van der Wee, eo le eena a supang hore sesosa ke bothata bo eketsehileng. O itse: "Batho ba bangata ba neng ba kentse letsoho liphuputsong tsena tsa pejana ba ne ba se ba ntse ba tšoeroe ke lefu lena, ka hona ha re tsebe hore na lintho tse sa tloaelehang li ne li le teng pele lefu le qala."
Ho ipapisitsoe le lithuto tsa pejana, bafuputsi ba bang ba khothalelitse hore bothata ba khatello ea maikutlo sechabeng bo bakoa ke tšebelisano lipakeng tsa bofokoli ba lefutso kapa bo fumanoeng ba tikoloho le tikoloho. Liphuputso tsa morao-rao li bontšitse hore bothata ba khatello ea maikutlo sechabeng bo kanna ba amana le ho se leka-lekane ha serotonin ea methapo ea kutlo. Lena ke lekhetlo la pele sistimi ea boko ea dopaminergic e hlahlojoa ka kotloloho.
"Le ha ho se na litlamorao tse tobileng kalafong ka lebaka la phuputso ena leha ho le joalo, ke karolo e 'ngoe ea bopaki bo bonts'ang ho se ts'oane ha likokoana-hloko, ho ka lebisang mekhoeng e mecha ea kalafo le temohisiso ka tšimoloho ea lefu lena," ho boletse Dr. van der Wee .
Ho latela Setsi sa Naha sa Bophelo ba kelello, lefu la ho tšoenyeha ka sechaba le ama batho ba baholo ba Amerika ba limilione tse 15 mme ke lefu la boraro le atileng haholo kelellong United States, kamora khatello ea maikutlo le ts'ebeliso ea joala. Karolo ea bohlokoa ea boteng bona ke tšabo ea ho hlahlojoa ke ba bang, ka tebello ea hore tlhahlobo e joalo e ka ba mpe le ho hlabisa lihlong. Hangata ho tsamaisana le maemo a sa feleng ebile ho sa tsamaee mme hangata ho lebisa ho nts'etsopele ea joala le khatello ea maikutlo. Boloetse bona bo hangata bo ba teng lilemong tsa bocha kapa boroetsaneng, empa bo ka hlaha ka nako efe kapa efe, ho kenyeletsa le bongoana.
Bangoli ba thuto ena ba kenyelletsa J. Frederieke van Veen, Irene M. van Vliet, Herman G. Westenberg, Lefapha la Psychiatry; le Henk Stevens, Peter P. van Rijk, Lefapha la Bongaka ba Nyutlelie, bohle ba tsoang ho Rudolf Magnus Institute of Neuroscience, University Medical Center Utrecht, Utrecht, Netherlands.
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Sengoloa sa Sengoloa:
1. NJ van der Wee, JF van Veen, H. Stevens, IM van Vliet, PP van Rijk, HG Westenberg. Ho eketsa Serotonin le Dopamine Transporter Bnding ho Psychotropic Medication-Naive Patients e nang le kakaretso ea khatello ea kelello ea khatello ea kelello e bonts'itsoeng ke 123I- - (4-Iodophenyl) -Tropane SPECT. Tlaleho ea Bongaka ba Nyutlelie, 2008; 49 (5): 757 DOI: 10.2967 / jnumed.107.045518
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