Ho bolela esale pele hore motho o na le botho bo botle ka litaba tse phetseng hantle ka mochini oa tlaase oa dopamine o tlama (2000)

Ke J Psychiatry. 2000 Feb; 157 (2): 290-2.

Laakso A, Vilkman H, Kajander J, Bergman J, paranta M, Solin O, Hietala J.

mohloli o moholo

Lefapha la Pharmacology le Clinical Pharmacology, Yunivesithi ea Turku, Finland. [imeile e sirelelitsoe]

inahaneloang

MORERO:

Li-receptor tse tlase tsa striatal dopamine D (2) tse kopantsoeng lithutong tse phetseng hantle tsa motho li amahanngoa le botho bo felletseng lithutong tse sebelisang positron emission tomografics (PET) le Karolinska Scales of botho. Bangoli ba ile ba fuputsa hore na ho na le kamano e tšoanang lipakeng tsa striatal dopamine transporter tse tlamang le tse senyehileng

METHODO:

Baithaopi ba 18 ba phetseng hantle ba nkile karolo phuputsong ea PET ka mofuta o khethehileng oa dopamine transporter ligand [(18) F] CFT ([(18) F] WIN 35,428) mme ba tlatsa foromo ea lipotso tsa Karolinska Scales of botho.

LIKOTSO:

Phapanyetsano ea dopamine e hlophisitsoeng ka lilemo-lemo e tlama ho putamen, empa eseng ka har'a caudate, e amanang hantle le lintlha tsa botho ba detachment, haholo-holo hemisphere e nepahetseng.

CONCLUSIONS:

Ho fumana hona ho tšehetsa khopolo ea hore "dopaminergic neurotransication" e amanang le botho bo senyehileng. Ho feta moo, kaha [(18) F] CFT e nahanoang e bonts'a letsoalo la lits'oants'o tsa methapo ea methapo ea methapo bokong, bangoli ba fana ka maikutlo a hore sebopeho sa methapo ea methapo ea methapo e ka ama litšobotsi tsa botho ba batho ba baholo.