Psychiatr Clin North Am 2002 Dec; 25 (4): 757-74
ea Schneier FR, Blanco C, Antia SX, Liebowitz MR.
Tleliniki ea Matšoenyeho a ho Tšoenyeha, Setsi sa Psychology ea New York State, New York, NY 10032, USA.
Boloetse ba ho tšoenyeha sechabeng bo loketse mohopolo oa ponahalo hobane o na le litšobotsi tse kang tsa ho qala, bokuli, 'me ha ho na moeli o tsoang ho matla o khethollang tloaelo e kholo ea khatello ea sechaba. Boloetse ba khatello ea maikutlo sechabeng bo bontšitsoe hore bo arabela litlhare tse ikhethileng tsa pharmacologic le boits'oaro, tse etsang hore ho khetholloe maemo a mang a ka bang holima bothata ba khatello ea maikutlo sechabeng bo bohlokoa ka lebaka la kalafo e ka bang teng. Likarolo tsa biologic tse amanang le bothata ba khatello ea maikutlo sechabeng le tsona li ka arolelanoa ka litsobotsi tse ts'oanang empa li sa tsejoe, joalo ka boits'oaro ba boits'oaro le sesole. Ho hlakisoa ha litšobotsi tse amanang le litsamaiso tse ikhethileng tsa biologic ho fana ka monyetla oa ho ntlafatsa kutloisiso ea semelo sa maemo ana. Bopaki bo matla bo teng ba hore bonyane mefuta e meng ea lihlong, ho qoba ho ba le bothata ba botho le khethollo ea khethollo li maemong a ho tšoenyeha ha sechaba. Bakeng sa mathata a mang a 'maloa a shebaneng haholo le papiso ea sechaba, lihlotšoana tsa bakuli li bonahala li na le mathata a khatello ea maikutlo sechabeng. Mathata ana a kenyelletsa khatello ea maikutlo e kholo (haholoholo atypical subtype), lefu la mmele la ho fokola ha mmele le mathata a ho ja. Mathata a mang a 'maloa a tšoauoang ke ho se sebetse hantle sechabeng kapa tšitiso, ho kenyeletsoa mathata a ts'ebeliso ea lithethefatsi (haholo-holo botahoa), paranoid, lefu la ho ferekana kelellong, lefu la autism le lefu la Asperger, le tsona li ka bonts'a tse ling li kopana le likarolo tsa khatello ea maikutlo sechabeng (mohlala, matšoenyeho a sechaba e le sesosa kapa bothata ba ts'ebeliso e mpe ea lithethefatsi, ho qoba ho ba le mathata a paranoid, disinhibiton sechabeng ho ferekana kelellong, le likhaello tsa puisano sechabeng ho autism le lefu la Asperger). Boloetse ba khatello ea maikutlo sechabeng bo boetse bo amahanngoa le mathata a mang a ho tšoenyeha ka kakaretso le phobias tse ling ka ho khetheha.
Mabapi le litšoaneleho, 'mele o ntseng o hola oa bopaki o hokahanya thibelo ea boits'oaro le ntho e sa tloaelehang le pherekano ea ho tšoenyeha ka mathata a sechaba. Mehato ea biologic ea dopamine system hypoactivity e hokahane le mathata a ho tšoenyeha ka sechaba, ho ts'oaroa ha mekhoa, le khaello e akaretsang ea moputso le ts'ebetso ea khothalletso.. E ntse e lokela ho hlakisoa, leha ho le joalo, hore na ts'ebetso ea ts'ebetso ea ts'ebetso ea ts'ebetso ea boko e tšoauoa hamolemo ke pherekano ea ho tšoenyeha ka boemo ba sechaba kapa mokhoa o mong o kenyelletsang khaello ea moputso oa sechaba kapa boits'ireletso ba sechaba. Mathata a ho tšoenyeha ka sechaba, ho soaba le boitšoaro bo ka sitisang batho bohle ho bonahala ba e-na le karolo ea liphatsa tsa lefutso, empa lipatlisiso tse eketsehileng lia hlokahala ho leka ho tseba hore na ho na le moea o joang o amanang le maemo ana.
Kamora nako, mohopolo o hlahang oa pherekano ea sechaba o hloka ho nonoa. Le ha mohopolo oa lefu le le leng la khatello ea maikutlo hajoale o na le ts'ebeliso ea bongaka, bangoli ba lumela hore ho tsepamisoa maikutlo feela mohopolong oa ts'ebetso e le 'ngoe e nang le maemo a mabeli a feteletseng - ho tloha ho ts'oaetso ea sechaba mania ho isa mofuteng o matla ka ho fetesisa oa matšoenyeho a sechaba, pherekano ea botho e qobang - e sa le pele ho nako ebile e lekanyelitsoe mabapi le lipatlisiso tsa etiologic. Mokhoa o mong ke ho nahana ka mefuta e mengata, mohlomong e fetang ka tsela ena sebakeng sena sa psychopathology ea sechaba. Litekanyo tsa motho ka mong li kanna tsa ipapisa le litšobotsi tse fapaneng tsa mantlha tsa "phenologic", kelo-hloko kapa biologic Mokhoa o tlase-tlase oa biologic o na le ts'episo ea ho khetholla spectra ka etiology e tloaelehileng e ka arabelang kalafo e ikhethileng. Ho ba le maikutlo a mangata mabapi le mohopolo oa ponahalo mothating ona ho ka thusa ho potlakisa kutloisiso ea rona ea matšoenyeho a sechaba le mathata a amanang le ona.
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