Pontšo ea dopamine ho lemalla lijo: karolo ea dopamine receptors ea D2 (2013)

Dopamine (DA) e laola boits'oaro ba maikutlo le bo susumetsang ka tsela ea mesolimbic dopaminergic. Liphetoho ho lets'oao la DA ho mesolimbic neurotransication ho lumeloa ka bophara ho fetola boits'oaro bo amanang le moputso mme ka hona, bo amana haufi le ts'ebeliso ea lithethefatsi. Bopaki ba morao-rao hona joale bo fana ka maikutlo a hore, joalo ka bokhoba ba lithethefatsi, botenya bo nang le boitšoaro bo qobelloang ba ho ja bo kenyeletsa moputso oa kelello, haholo-holo potoloho e kenyelletsang likarolo tse nyane tsa dopaminergic. Palo e ntseng e eketseha ea datha ho tsoa lithutong tsa ho nahana ka batho, hammoho le tlhahlobo ea liphatsa tsa lefutso, e bontšitse hore batho ba batenya le lithethefatsi tsa lithethefatsi ba tloaetse ho bonts'a polelo e fetohileng ea li-receptor tsa DA D2 libakeng tse itseng tsa boko, le hore likarolo tse tšoanang tsa boko li hlahisoa ke lijo tse amanang le lijo le lithethefatsi. lintlha tse amanang. Tlhahlobo ena e shebisisa mesebetsi ea sistimi ea DA, e tsepamisitse maikutlo holima toloko ea 'mele le karolo ea DA D2 receptor ho hlahisa ts'ebeliso ea lijo. [Litlaleho tsa BMB 2013; 46 (11): 519-526].