Nako ea mokokotlo. 2010 Aug 1; 52 (1): 277-83. Doi: 10.1016 / j.neuroimage.2010.04.019.
Hermans EJ, Bos PA, Ossewaarde L, Ramsey NF, Fernández G, van Honk J.
Setheo sa Donders bakeng sa Brain, Cognition and Behavior, Radboud University Nijmegen, Nijmegen, Netherlands. [imeile e sirelelitsoe]
inahaneloang
Bopaki ba Correlational ho batho bo bontša hore litekanyetso tsa androgen ea testosterone li amana hantle le matla a ho matlafatsa le ho hlolisana ho khanna. Mefuta e tšoanang ea li-anabolic-androgenic steroid (AAS) e hlekefetsoa ka bongata, 'me lithuto tsa liphoofolo li bontša hore litoeba li itšoaela testosterone. Litlhokomeliso tsena li fana ka maikutlo a hore testosterone e fana ka litlamorao tsa ts'ebetso litseleng tsa mesolimbic dopaminergic tse kenelletseng ts'ebetsong ea ts'usumetso le taolo ea ts'ebetso. Leha ho le joalo, ha ho na datha ho batho e tšehetsang khopolo ena. Re sebelisitse imagingance resonance imaging (fMRI) e sebetsang ho etsa lipatlisiso ka litlamorao tsa tsamaiso ea testosterone mosebetsing oa neural libakeng tsa terminal tsa tsela ea mesolimbic. Ka moralo oa "cros temple" o laoloang ke batho ba sa boneng habeli, basali ba phetseng hantle ba 12 ba ile ba fumana tsamaiso e le 'ngoe ea .5 mg ea testosterone. Nakong ea ho hlahlojoa ha MRI, barupeluoa ba ile ba etsa mosebetsi oa ho lieha ho khothaletsa chelete, o tsejoang ka ho khothaletsa ts'ebetso ea "ventral striatum" nakong ea tebello ea moputso. Liphetho li bonts'a phello e ntle ea testosterone karabong e arohaneng ho "ventral striatum" ho litheko tse bonts'ang meputso e teng ntle le e seng moputso. Haholo, phello ena e sebelisana le maemo a ipatileng a takatso ea takatso ea takatso: batho ba nang le takatso e fokolang ea takatso ea takatso ba bontšitse kholo e kholo ea testosterone empa ba bile le likarabo tse nyane kamora ho hlaseloa ha placebo. Kahoo, thuto ea hona joale e fana ka ts'ehetso ea hypothesis ea hore testosterone e ama ts'ebetso libakeng tse amanang le mesopimbic dopamine system empa e fana ka maikutlo a hore litlamorao tse joalo li kanna tsa ba ho batho ba nang le takatso e tlase ea takatso ea takatso.. Ka ho bonts'a mochini o ka bang matlafatso ea ts'ebeliso ea androgen, liphetho tsa hona joale li ka ba le litlamorao kutloisisong ea rona ea pathophysiology ea ts'ehetso ea AAS.
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