Nutr Neurosci. 2017 Apr 11: 1-9. Doi: 10.1080 / 1028415X.2017.1313583.
Kim JY1, Kim D1,2, Park K3, Lee JH1, Jahng JW1.
inahaneloang
LIPOTSO:
Phuputso ena e ile ea etsoa ho lekola litlamorao tsa thobalano tsa phallo e fumanehang habonolo ea lijo (HPF) nakong ea bocha ho buoa ka methapo ea kutlo le khatello ea maikutlo joalo ka boits'oaro ba litoeba.
LITLHAHISO:
Malinyane a banna le basali ba Sprague-Dawley ba ne ba e-na le monyetla oa ho fumana li-cookie tse nang le mafura a mangata (HPF) ho tloha matsatsing a phomolo ea 28 ntle le ad libitum chow, mme lihlopha tsa taolo li fumana chow. Maemo a lijo a ile a tsoela pele ho pholletsa le nako eohle ea liteko, 'me mehato ea methapo le boitsoaro e entsoe lilemong tsa bocha. Likhoto li ile tsa etsa mosebetsi oa ho emella, tsa phahamisoa le ho ba le liteko tse ngata tsa ho sesa. Maemo a Corticosterone nakong ea 2 h ea khatello ea maikutlo a thibelo a ile a hlahlojoa ka radioimmunoassay, le polelo ea ΔFosB le neurotrophic factor (BDNF) ka har'a nucleus accumbens (NAc) ka tlhahlobo ea blot ea Bophirimela.
LIKOTSO:
Ho fihlella ha Cookie ha hoa ka ha ama boima ba 'mele le ho kenella ka har'a caloric ka bongata ho bong ba bona; leha ho le joalo, e ile ea eketsa depoperitoneal fat depot feela ho ba batona. Nako e sebelisitsoeng matsohong a bulehileng nakong ea teko e phahameng ea maze e ile ea fokotseha 'me ho se sebetse hantle nakong ea liteko tsa ho sesa tse qobelloang ho ile ha eketseha ho ba batona ba fuoang li-cookie, empa eseng ho basali ba feptjoitsoeng ke cookie. Kameho e ka sehloohong ea boemo ba lijo ho keketseho ea corticosterone e bakiloeng ke khatello ea maikutlo e ile ea bonoa ho banna, empa eseng ho basali, mme phihlello ea cookie e eketsehile polelo ea BDNF ho NAc feela ho banna.
CONCLUSIONS:
Keketseho ea polelo ea BDNF ho NAc le depo ea mafura, ntle le khatello ea khatello ea mokokotlo, e ka bapala likarolo ho pathophysiology ea khatello ea maikutlo le / kapa boits'oaro bo ts'oanang le bo ts'oaroang ke ts'ebetso ea cookie.
LINKOTSO: Corticosterone; Ho ja lijo; Li-bokella tsa nyutlelie; Khatello ea maikutlo
PMID: 28399791
DOI: 10.1080 / 1028415X.2017.1313583
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