Ha litekanyetso tsa botenya li ntse li eketseha lefatšeng ka bophara le tšebeliso e ngata ea tsoekere e nkuoa e le motsoako o tobileng, patlo e se e le bakeng sa kalafo ho khutlisa mokhoa ona. Joale thuto ea pele-pele e tataisoang ke QUT e kanna ea ba le karabo
Univesland University of Technology
Ha litekanyetso tsa botenya li ntse li eketseha lefatšeng ka bophara le tšebeliso e ngata ea tsoekere e nkuoa e le motsoako o tobileng, patlo e se e le bakeng sa kalafo ho khutlisa mokhoa ona. Joale thuto ea pele-pele e tataisoang ke QUT e kanna ea ba le karabo.
Setsebi sa thuto ea methapo, Moprofesa Selena Bartlett oa Setsi sa QUT sa Bophelo le Biomedical Innovation o boletse hore phuputso e sa tsoa phatlalatsoa ke koranta ea lipatlisiso ea machabeng. PLOS ONE, e bontša lithethefatsi tse sebelisoang ho phekola bokhoba ba boko ba nicotine li ka sebelisoa ho phekola bokhoba ba tsoekere ho liphoofolo.
Sengoliloeng sena se kopana le pampiri e 'ngoe ea sehlopha - Tšebeliso e telele ea Sucrose ho Binge-Like Manner, e fetola Morphology ea Medium Spiny Neurons ho Nucleus Accumbens Shell - e phatlalatsoang ho Frontiers in Behaeveal Neuroscience. E bontša hore ho noa tsoekere nako e telele ho ka baka mathata a ho ja le ho ama boits'oaro.
"Lipalo tsa morao-rao tsa Mokhatlo oa Lefatše oa Bophelo li re bolella hore batho ba limilione tse likete tse 1.9 lefatšeng ka bophara ba nonne haholo, 'me ba limilione tse 600 ba nkoa ba le batenya," ho boletse Moprofesa Bartlett ea lulang Setsing sa Lipatlisiso sa Translational.
“Ts'ebeliso e ngata ea tsoekere e netefalitsoe hore e kenya letsoho ka kotloloho ho nona. Ho bonts'itsoe hape hore hangata e phahamisa maemo a dopamine a laolang moputso oa boko le litsi tsa monyaka ka tsela e ts'oanang le lithethefatsi tse ngata tsa tlhekefetso ho kenyeletsoa koae, cocaine le morphine.
“Kamora tšebeliso ea nako e telele, sena se lebisa ho se fapaneng, phokotso ea maemo a dopamine. Sena se lebisa ts'ebelisong e phahameng ea tsoekere ho fumana moputso o tšoanang.
“Re boetse re fumane hore hammoho le kotsi e eketsehileng ea ho nona, liphoofolo tse bolokang ts'ebeliso e phahameng ea tsoekere le ho itlopa joala ho fihlela li le batho ba baholo le tsona li ka tobana le litlamorao tsa methapo le kelello tse amang maikutlo le tšusumetso.
"Phuputso ea rona e fumane hore Tsamaiso ea Lijo le Lithethefatsi (FDA) e lumelletse lithethefatsi tse kang varenicline, khoebo ea meriana e fanoang ke ngaka e le Champix e sebetsanang le bokhoba ba nicotine, e ka sebetsa ka tsela e ts'oanang ha ho tluoa litakatsong tsa tsoekere."
Mofuputsi oa PhD Masroor Shariff o re liphuputso li boetse li beha li-sweeteners tsa maiketsetso tlasa sepakapaka.
"Ho khahlisang ke hore thuto ea rona e fumane hape hore lino-mapholi tse iketselitsoeng tse kang saccharin li ka hlahisa litlamorao tse ts'oanang le tseo re li fumaneng ka tsoekere ea tafoleng, ho totobatsa bohlokoa ba ho lekola botjha kamano ea rona le lijo tse tsoekere ka nngoe," ho boletse Mong Shariff.
Moprofesa Bartlett o re varenicline e sebelitse e le neuronal nicotinic receptor modulator (nAChR) mme litlamorao tse ts'oanang li ile tsa bonoa le lithethefatsi tse ling tse kenyeletsang mecamylamine le cytisine.
O ile a re: "Joalo ka lithethefatsi tse ling tsa tlhekefetso, ho ikhula khafetsa pepeneneng ea sucrose ho ka baka ho se leka-lekane ha maemo a dopamine mme ho be thata joalo ka ho tloha ho" batang ho bata "ho bona.
"Ho hlokahala lithuto tse ling empa liphetho tsa rona li fana ka maikutlo a hore litlhare tsa NAChR tse amoheloang ke FDA li ka emela leano le lecha la kalafo ho sebetsana le seoa sa botenya."
Ho ka baloa leqephe le felletseng la Neuronal Nicotinic Acetylcholine Receptor Modulators Fokotsa tsoekere. PLOS ONE.
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QUT ke karolo ea sehlopha sa naha se kopaneng sa liunivesithi tse hlano tse kholo tsa Australia tse bopa ATN (Australia Technology Network of University).
Setsoalle sa mecha ea litaba:
Amanda Weaver, QUT Media, 07 3138 1841, [imeile e sirelelitsoe]
Kamora lihora: Rose Trapnell, 0407 585 901, [imeile e sirelelitsoe]
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