Ka mokhoa o moholo o koahelang li-substrate tsa neuronal tsa reactivity ho lithethefatsi, papali ea chelete, lijo le litabeng tsa thobalano: Tlhahlobo e feletseng ea meta (2016)

Ho kopana hape meputsong ea tlhaho le ea sechaba ho bohlokoa bakeng sa boitšoaro bo susumetsang. Leha ho le joalo, ho tloaela ho etsa joalo ka meputso ea lithethefatsi ho ka etsa hore le litakatso tsa bona litabeng tse lemalloang. Hore na meputso ea lithethefatsi le tlhaho e arolelana likarolo tsa neural ha e tsejoe. Morero oa thuto ena ke ho etsa tlhahlobo e akaretsang ea lithuto tsa neuroimaging mabapi le lithethefatsi, papali ea chelete le maikutlo a tlhaho (lijo le thobalano) ho khetholla likarolo tse tloaelehileng le tse ikhethileng tsa neural tsa ho sebetsa hape ka litheko tsa lithethefatsi le tlholeho. Lithuto tsa Neac cac reacaction li ile tsa khethoa bakeng sa tlhahlobo ea meta ka litekanyetso tsa monyetla oa ts'ebetso, tsa lateloa ke maikutlo le tlhahlobo e kopaneng ea mekhoa ea karabelo ea methapo ea kutlo. Lintlha tse tsoang liphuputsong tsa 176 (batho ba 5573) li fana ka maikutlo a ho pharalla ha mekhoa ea karabelo ea neural mabapi le mekhoa eohle e lekiloeng ea moputso. Reacaction e tloaelehileng ea meputso ea tlhaho le ea lithethefatsi e bontšitsoe ke likarabo tse peli tsa tlhaho ka hare ho citrate gyrus, insula, hlooho ea sefahleho, gyrus e ka tlase e ka pele, gyrus e bohareng le e ka pele. Leha ho le joalo, mekhoa ea lithethefatsi e boetse e hlahisa mekhoa e fapaneng ea ts'ebetso ho gial ea medial frontal, gyrus e bohareng ea nakoana, posterior cingulate gyrus, mmele oa caudate le putamen. Cards ea moputso oa tlholeho (oa thobalano) e kentse ts'ebetso e ikhethang ea pulvinar thalamus. Likarolo tse tlase tsa ho kopana hape hoa mofuta oa cue ho joala, lithethefatsi tsa tlhekefetso, lijo, thobalano le papali ea chelete li ngata haholo 'me li na le marang-rang a sebetsanang le moputso, likarabo tsa maikutlo le boikoetliso. Sena se fana ka maikutlo a hore ho lakatsa ka mokhoa o kopanetsoeng ho kenyelletsa mekhoa e sa ikhethileng bakeng sa lits'oaetso tse lemalloang empa e tšoana le ho ts'oaroa ha litsela tsa tlhahisoleseling mabapi le moputso, likarabo tsa maikutlo, ho se hopole lintho tse senang kelello le boits'oaro bo hlokisang botsitso.

PMID: 27397863

DOI: 10.1016 / j.euroneuro.2016.06.013