Fetolela Psychiatry. 2017 Apr 4; 7 (4): e1085. Doi: 10.1038 / tp.2017.55.
Fujimoto A1,2, Tsurumi K1, Kawada R1, Murao T1, Takeuchi H1, Murai T1, Takahashi H1,2.
inahaneloang
Boloetse ba papali ea chelete (GD) hangata bo nkuoa e le bothata ba ho khetha likotsi tse joalo ka likotsi. Leha ho le joalo, matšoao a GD a ke ke a utloisisoa ka botlalo ke pono ena ea semelo. Thutong ea hajoale, re nahanne hore bakuli ba GD le bona ba na le bothata ba taolo e feto-fetohang ea boits'oaro ba likotsi (ts'ebeliso ea leano le itšetlehileng ka mmuso), mme re ikemiselitse ho fuputsa mekhoa e tlisang likotsi tse sa tloaelehang tsa GD. Ho rarolla bothata bona, re lekile bakuli ba GD ntle le comorbidity (sehlopha sa GD: n = 21) le barupeluoa ba taolo e phetseng hantle ba nang le taolo (sehlopha sa HC: n = 29) mosebetsing oa mehato e mengata oa papali ea chelete, moo bankakarolo ba neng ba hloka ho hlakola 'block' quota '(ho hlokahala liuniti ho hlakola boloko, li-unit tsa 1000-7000) likhethong tse 20, mme ba etsa liteko tse sebetsang tsa imaging resonance imaging (fMRI). Tlhahlobo ea boits'oaro e hlile e senotse phetoho e sa fetoheng ea maemo a kotsi sehlopheng sa GD; sehlopha sa GD se ile sa hloleha ho qoba khetho e kotsi maemong a itseng a palo (boemo ba sekhahla se tlase), moo leano le kotsi le neng le sa nepahala ho rarolla sekhahla. Ka hona, tlhahlobo ea fMRI e totobalitse ts'ebetso e fokotsehileng ea dorsolateral prefrontal cortex (dlPFC), e bileng le tšusumetso e matla ho fetoheng ha kelello. Ho tsebo ea rona, thuto ea hajoale e fane ka bopaki ba pele bo matla ba khaello ea ntlafatso ea leano le itšetlehileng ka mmuso ho GD. Ho tsepamisa mohopolo taolong e tenyetsehang ea maikutlo a kotsi tlasa sekhahla ho ka kenya letsoho kutloisisong e ntle ea psychopathology ea li-GDs.
PMID: 28375207
PMCID: PMC5416696
DOI: 10.1038 / tp.2017.55
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