Biol Psychiatry. 2017 Jun 16. pii: S0006-3223 (17) 31672-4. Doi: 10.1016 / j.biopsych.2017.06.010.
van Holst RJ1, Sescousse G2, Janssen LK2, Janssen M3, Berry AS4, Jagust WJ4, Ho fepa R5.
inahaneloang
LITLHAHISO:
Motsoako o reng dopamine o bapala karolo ea bohlokoa ho pathophysiology ea ho becha ha methapo ea methapo o atile. Leha ho le joalo, ha ho na bopaki bo tobileng ba phapang ea phapang pakeng tsa papali ea papali ea chelete le lithuto tse laoloang hantle mabapi le phetisetso ea dopamine maemong a se nang lithethefatsi. Mona re fana ka bopaki ba hypothesis ena ka ho bapisa bokhoni ba dopamine syntheska kahare le likarolo tsa "striatum" tsa "GNUMX"
LITLHAHISO:
Sena se fihletsoe ho sebelisoa [18F] fluoro-levo-dihydroxyphenylalanine dynamic positron emission tomography scans le libaka tse khahlang tse khahlisang tse ileng tsa ts'oaroa ka matsoho ho ipapisitse le tlhahlobo e bonoang ea sebopeho sa motho sa sebopeho sa matla a matla a khoheli.
LIKOTSO:
Liphetho tsa rona li bonts'a bokhoni ba dopamine synthesis bo ile ba eketseha ho tsa papali ea papali ea chelete ho bapisoa le lithuto tse phetseng hantle. Dopamine synthesis e ne e le 16% e phahame ho 'mele oa caudate, 17% e phahame ho dorsal putamen, le 17% e phahame kahare ho "striatum" ea li-gambler ho bapisoa le lithuto tse laoloang. Ho feta moo, bokhoni ba dopamine synthes ka har'a dorsal putamen le hlooho ea caudate bo ne bo amana hantle le tšekamelo ea papali ea chelete ho becha.
CONCLUSIONS:
Ha li kopantsoe hammoho, liphetho tsena li fana ka bopaki bo matla ba ho eketseha ha dopamine dopamine papaling ea papali ea chelete.
LINKOTSO: Tlatsetso; Dopamine; Ho becha; Neuroimaging; Moputso; [(18) F] DOPA
PMID: 28728675
DOI: 10.1016 / j.biopsych.2017.06.010
;
