Biol Psychiatry Cogn Neurosci Neuroimaging. 2017 Mar;2(2):188-195. doi: 10.1016/j.bpsc.2016.03.001.
Yip SW1, Morie KP2, Xu J2, Rableable3, Malison RT4, Carroll KM2, Potenza MN5.
inahaneloang
LITLHAHISO:
Ho tšoana pakeng tsa bokhoba ba lithethefatsi le lithethefatsi. Leha ho le joalo, papiso e tobileng ea neurobiological lipakeng tsa likhathatso tse lemalloang ke seoelo. Boikemisetso ba bothateng bo ikhethileng (kapa ho haella ha hona) ha liphetoho lipakeng tsa li-Micrope tse tšoeu li tla ntšetsa pele kutloisiso ea pathophysiology ea lithethefatsi.
LITLHAHISO:
Re bapisitse likarolo tsa maiketsetso tse tšoeu tse pakeng tsa batho ba nang le bothata ba papali ea chelete (GD; n = 38), ts'ebeliso ea ts'ebeliso ea k'hok'heine (CUD; n = 38) le papiso e phetseng hantle (HC; n = 38) bankakarolo, joalo ka ha ho lekantsoe ho sebelisoa matla a khoheli a boima. Litšoantšo tsa resonance (dMRI). Ho fana ka khakanyo e nepahetseng ea ho hasana kahare ho libaka tsa meralo e rarahaneng (mohlala, lipampitšana tsa cortico-limbic), litlhahlobo li ile tsa etsoa ka mokhoa oa cross-fiber o kenyelletsang mohlala oa tikoloho (tbss_x). Likhakanyo tsa anisotropy bakeng sa litloaelo tsa mantlha le tsa bobeli tsa fiber li bapisoa le li-ANOVA tse lokisitsoeng bakeng sa papiso e mengata ho pholletsa le sebaka ho sebelisa ntlafatso ea sehlopa se se nang moeli (pFWE <.05).
LIKOTSO:
Phello e kholo ea sehlopha ho anisotropy ea sekhahla sa fiber ea kahare kahare ho mokokotlo oa kahare o ka letsohong, corona radiata, radiation e kholo le ea morao-rao ea thalamic, e kenyang ho fokotsa lenane har'a barupeluoa ba GD le CUD ha ho bapisoa le barupeluoa ba HC. Ha ho phapang pakeng tsa mehato ea anisotropy e fumanoeng lipakeng tsa GD le batho ba CUD.
CONCLUSIONS:
Ena ke thuto ea pele ea ho bapisa indices ea infusion ka kotloloho lipakeng tsa litekanyetso tsa boits'oaro le lithethefatsi le thuto e kholo ka ho fetisisa ea DMRI ea GD. Seo re se fumaneng se bonts'a liphetoho tse tšoanang le tse tšoeu tse amanang le bokhoba ba tahi tse ke keng tsa bakoa feela ke ho pepesehela lithethefatsi kapa joala, ka hona e ka ba mokhoa o ka re hlaselang habonolo bakeng sa mathata a lemalloang.
LINKOTSO: bothata ba tšebeliso ea joala; tlhekefetso ea boitšoaro; infusion tensor imaging (DTI); ho qhekella; ho becha ka methapo; tlhekefetso ea tšebeliso ea lithethefatsi
PMID: 28367515
PMCID: PMC5373810
DOI: 10.1016 / j.bpsc.2016.03.001
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