Biol Psychol. 2016 Dec 20. pii: S0301-0511 (16) 30375-1. Doi: 10.1016 / j.biopsycho.2016.12.012.
Koopmann A1, Schuster R2, Mofumahali F2.
inahaneloang
Ghrelin, e lokolloang haholo ka mpeng, ke molaoli oa bohlokoahali oa orexigenic oa lijo, o etsa hore motho a be le takatso ea lijo, a ntlafatse ho rata le ho hlakola lihormone tsa kholo. Ntle le hypothalamus, ghrelin receptors (GHS-R1A) e boetse e hlahisoa tsamaisong ea mesolimbic dopaminergic, e eketsang monyetla oa hore ghrelin e bapala karolo ea bohlokoa ho regulation ea meputso bakeng sa likotsi tsa ts'ebeliso ea lithethefatsi joalo ka ts'ebeliso ea joala, haholoholo ka ho kenya ts'ebetsong moputso oa cholinergic-dopaminergic khokahano. Thutong ena re shebisisa tšusumetso ea moea oa moea o mabapi le nts'etsopele le ho boloka bokhoba ba tahi / taolo ea joala, tšebeliso ea joala, takatso ea joala le ho itlopa joala, ho leka ho hokahanya lithuto le liteko tsa bongaka mabapi le kamano e khahlisang lipakeng tsa taolo ea takatso ea lijo, moputso le bokhoba ba joala. Ho kopanya data e teng ea preclinical le ea bongaka ho ghrelin antagonism, haholo-holo ho GHS-R1A receptor ho mesolimbic dopaminergic pathways, ho ka senola sepheo se secha le sa boqapi bakeng sa kalafo ea ts'epahalo ea joala nakong e tlang.
LINKOTSO: Ghrelin; ho lemalla joala / ho lemalla joala; tšebeliso ea joala; ho lakatsa joala; lefu la tšebeliso ea joala; ho itlopa joala; ethanol
PMID: 28011402
DOI: 10.1016 / j.biopsycho.2016.12.012
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