Resin ea Boko. 2014 Dec 18. pii: S0006-8993(14)01708-9. doi: 10.1016/j.brainres.2014.12.024.
MOorman DE1, James MH2, McGlinchey EM3, Aston-Jones G2.
inahaneloang
Cortex ea pele e bapala karolo ea bohlokoa ho fetoleng kelello le boits'oaro. Boithuto bo bongata bo bonts'itse hore medial prefrontal cortex (mPFC) e bapala karolo ea bohlokoa ho batleng, ho felleng, le ho khutlisetsoa hoa koae ea koae ka mefuta ea phetetso. Likarolo tsa mPFC li shebahala li bapala karolo tse ikhethang ho boits'oaro bona, bo khothalletsoang hore prelimbic cortex (PL) ho khanna ho ts'oana ha koae 'me infralimbic cortex (IL) e khothalletsoe ho hatella ho batla koae ka mor'a ho felisoa. Dichotomy ena ea ts'ebetso ea mPFC e kanna ea ba kakaretso, joalo ka ha likarohano tse tšoanang tsa dorsal-ventral li teng bakeng sa polelo vs. ho felisoa hoa boemo ba tšabo. Leha ho le joalo, liphetho tse ling li bonts'a hore karolo ea li-neuron tsa mPFC ts'ebetsong ea moputso e rarahane ho feta mokhoa o bonolo oa PL-batla vs IL-extinguish dichotomy. Ka bobeli ba PL le IL ba bontšitsoe ho khanna le ho thibela ho batloa ha lithethefatsi (le mefuta e meng ea boits'oaro) ho latela lintlha tse fapaneng ho kenyeletsa maemo a boitšoaro, nalane ea lithethefatsi ea phoofolo, le mofuta oa lithethefatsi tse entsoeng lipatlisiso. Tlholo ena ea ho fumana lintho e ka bonts'a li-subcircuits tse ngata ho e 'ngoe ea libaka tsena tsa PFC tse ts'ehetsang mesebetsi e ikhethang. E kanna ea bonts'a 'nete ea hore mPFC e bapala karolo e kopantsoeng ho hlophiseng kelello le boits'oaro, ho kenyelletsa le tse fetang ka ho batla le koae. Mona re bua ka lipatlisiso tse lebisang ho khopolo-taba ea hore dorsal le ventral mPFC ka ho fapana li laola ho batla lithethefatsi le ho timela. Re hlahisa sephetho sa morao-rao se bitsang mofuta o hlakileng oa PL vs. IL dichotomy ho belaela. Kamora nako, re nka mesebetsi e meng bakeng sa mPFC e tsamaellanang le ts'ebetso ea karabelo le thibelo mme ho fapana le moo re kenyelletsa boiphihlelo bo rarahaneng ba ho tsebahala boo MPFC e ananeloang haholo.
Sengoliloeng sena ke karolo ea Sengoloa se Ikhethileng se bitsoang Li-circuits tsa Tlatsetso.
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