Ho kenella ka mokhoa o khethollang ho sebetsa ha setamen molemong oa bocha le bothata ba ho bapala lipapali tsa inthanete (2014)

• ¹Setsi sa Melbourne Neuropsychiatry, Lefapha la Psychiatry, Univesithi ea Melbourne le Melbourne Health, Parkville, Victoria, Australia; Florey Setsi sa Neuroscience le Mental Health, Parkville, Victoria, Australia; Karolelano ea Psychology ea bana le ea lilemong tsa bocha, Lefapha la Mahlale a kelello, Sepetlele sa Sechaba sa Seoul Seoul, Rephaboliking ea Korea.
• ²Setsi sa Melbourne Neuropsychiatry, Lefapha la Psychiatry, Univesithi ea Melbourne le Melbourne Health, Parkville, Victoria, Australia.
• ³Lefapha la Nts'etsopele ea Bana le Lithuto tsa Lelapa, K'holejeng ea Kholo ea Batho, Seoul University, Seoul, Rephabliki ea Korea.
• ⁴Seoul-Top Psychchiatric Clinic, Gyeonggi, Rephabliking ea Korea.
• ⁵Lenaneo la Interdisciplinary (Sekolo sa thuto ea bongoana sa Majoro), K'holejeng ea Thuto, Univesithi ea Seoul ea Seoul, Seoul, Rephabliki ea Korea.
• ⁶Lefapha la Thuto (Tlhokomelo ea Boeletsi ea Thutelo), K'holejeng ea Thuto, Univesithi ea Seoul ea Seoul, Seoul, Rephabliki ea Korea.
• ⁷Karolelano ea Psychology ea bana le ea lilemong tsa bocha, Lefapha la Mahlale a kelello, Sepetlele sa Sechaba sa Seoul Seoul, Rephaboliking ea Korea.
• ⁸Lefapha la Nts'etsopele ea Bana le Lithuto tsa Lelapa, K'holejeng ea Kholo ea Batho, Seoul University, Seoul, Rephabliki ea Korea. Aterese ea elektroniki: [imeile e sirelelitsoe].

Li-circuits tsa bort cortico-striatal li bile le tšusumetso ho sa feleng lithutong tsa mathata a amanang le bokhoba ba tahi. Re sebelisitse tlhahlobo e ts'epahalang e thehiloeng ho peo ea ts'ebetso ea boko ba naha ho phomola ka botlalo likarolo tse ka tlase tsa ts'ebetso ea ts'ebetso ea striatal e kenelletseng bothateng ba lipapali tsa marang-rang. Har'a bacha ba leshome le metso e 'meli ba batona ba nang le bothata ba lipapali tsa marang-rang le taolo e ntle ea letsoho la 11 le e tsamaellanang le bong, re ile ra hlahloba ho se tšoane ha lihlopha ho arolelanoang ha likarolo tsa methapo ea methapo le li-putamen, hammoho le mokhatlo oa bana indices tsa khokahano le mehato ea boitšoaro ea ts'ebeliso ea marang-rang. Bacha ba nang le bothata ba lipapali tsa marang-rang ba bontšitse ho fokotsoa haholo ho hokahanngoeng ha dorsal putamen ka ho sebetsa le posterior insula-parietal operculum. Nako e eketsehileng e sebelisitsoeng lipapaling tsa marang-rang e boletse esale pele khokahano e kholo ea ts'ebetso lipakeng tsa dorsal putamen le li-cortices tse peli tsa mantlha tsa bongoaneng ho bacha ba nang le ts'oaetso ea lipapali tsa marang-rang, le botebo bo tlase bo sebetsang pakeng tsa dorsal putamen le li-cortices tsa sensorimotor tse peli. Khokahano e sebetsang ea dorsal putamen e ne e fapane haholo ebile e fapane haholo ho bacha ba nang le bothata ba lipapali tsa marang-rang. Se fumanoeng se fana ka tlhahiso ea hore na ho ka ba le mofuta ofe oa mathata a lipapali tsa marang-rang.