Phello ea motlakase oa motlakase o kopantsoeng le ho kenella ka kelello litabeng tsa matšoao a kelello le P50 ea mokhoa o hlakileng oa ho hlekahleka ho bakuli ba nang le bothata ba ho lemalla ho sebelisa inthanete (2017)

• Li Hui^a,
• Jin Rongjiang^b,
• Yuan Kezhu^b,
• Zheng Bo^c,
• Zheng Zhong^d,
• Luo Ying^e,
• Ee Hua^b,
• Huang Bingjie^b,
• Zhu Tianmin^b,,

http://dx.doi.org/10.1016/S0254-6272(17)30025-0

inahaneloang

LEHLOHONOLO

Ho boloka liphello tsa phekolo ea motlakase (EA) li kopantsoe le ho kenella ka kelello ka matšoao a ho khutsisa kapa ho ba le bothata ba kelello le matšoao a kelello a ho tepella maikutlo kapa ho tšoenyeha le P50 ea Auditory Evoked Potential (AEP) ka ho lemalla bothata ba ho lemalla lithethefatsi (IAD).

METHODA

Likarolo tse lekholo le mashome a mabeli tsa IAD li arotsoe ka likarolo sehlopha sa EA, sehlopha sa psycho-intervention (PI) le sehlopha se phekileng (EA hammoho le PI). Bakuli ba sehlopha sa EA ba ile ba tšoaroa ka EA. Bakuli ba sehlopha sa PI ba ne ba tšoaroa ka thobalano le kalafo ea boitšoaro. Bakuli ba sehlopha sa EA le sehlopha sa PI ba ne ba tšoaroa ka electro-acupuncture hammoho le ho kenella maikutlong. Lintlha tse ngata tsa IAD, lenane la lipalo tsa matšoao a 90 (SCL-90), latency le boholo ba P50 ea AEP li ne li lekantsoe pele ho kalafo le ka morao kalafo.

LIPOTSO

Litho tse ngata tsa IAD ka mor'a hore phekolo e fokotsehe haholo lihlopheng tsohle (P <0.05), mme lipalo tsa IAD sehlopheng sa EA le PI li ne li le tlase haholo ho feta tse lihlopheng tse ling tse peli (P <0.05). Boholo ba SCL-90 bo bokane mme ntlha ka 'ngoe kamora kalafo sehlopheng sa EA le PI e fokotsehile haholo (P <0.05). Kamora kalafo sehlopheng sa EA hammoho le PI, sebaka sa bophahamo ba S1P50 le S2P50 (S1-S2) se eketsehile haholo (P <0.05).

QETELLO

EA e kopantsoe le PI e ka fokotsa matšoao a kelello a bakuli ba IAD, 'me mochine ona o ka' na oa amahanngoa le keketseho ea kutlo ea kelello ea kutloisiso ea ho etsa mosebetsi.

Mantsoe a bohlokoa

• Bothata ba bokhoba ba ts'ebeliso ea inthanete;
• Electroacupuncture;
• Ho kenella ha kelello;
• Boitšoaro bo hlokolosi;
• E khonahala

SELELEKELA

Ho lemalla taolo ea marang-rang (IAD) ke boemo bo kenyelletsang mathata a kelello a ho mamellana ka matla, matšoao a ho khaola, ho ferekana maikutlong, discontinuance ea kamano, jj. Le li-syndromes tsa serial tse kang bophelo bo botle ba mmele le ts'ebetso ea methapo ea methapo.^{1 ;  2} IAD e ka ba le tšusumetso e mpe haholo kholisong e tloaelehileng ea kelello mme ea lebisa ho li-syndromes tsa serial tse kang ho khathatseha maikutlong, mathata a boitšoaro, khatello ea kelello, jj.³

Ho tloha joale ho ea pele, mehato ea ho kenella bakeng sa IAD haholo-holo e kenyelletsa kalafo ea pharmacologic, kalafo ea boits'oaro ba kelello, lipuisano tse susumetsang le tse ling.⁴ Boithuto bo 'maloa bo boetse bo khothalelitse hore electro-acupuncture e na le phello e ntle ea kalafo ho IAD,^{5 ;  6} empa ha ho na bopaki bo lekaneng ba ho hlalosa mochine oa phekolo. Hajoale lipatlisiso tsa neuropsychological li bontšitse hore, bofokoli ba maikutlo a ho ferekanya kelello (SG) bo ka baka mathata a mangata a kelello joalo ka khatello ea maikutlo, schizophrenia le khatello ea maikutlo.^{7 ;  8} IAD e kanna ea ba le motheo o tloaelehileng oa neuropsychological ka mathata ana. SG e bua ka thepa ea kelello ho thibela mohopolo o sa amaneng le maikutlo, e leng ts'ebetso ea bohlokoa ea kelello. SG hangata e amahanngoa le lintlha tse amanang le ketsahalo tse ka lekanngoang ke P50, e leng e 'ngoe ea litekanyo tse sebelisitsoeng hampe tsa li-electro-neurophysiological. P50 e bua ka boholo bo phahameng ba maqhubu a pakeng tsa 30ms le 90ms bokong kamora ho hlohlona. Ke ts'ebetso eo boko bo nang le karabelo e ithibelang ho eona hape ka mor'a e 'ngoe ea matlafatso ea pele. Kahoo P50 ea li-potentials tse hlahisang li-auditory (evangeli) li ka bontša ts'ebetso ea inhibition le ts'ebetso ea mantlha ea SG ea boko.⁹ Re ipapisitse le sena, re nahana hore phetoho ea P50 pele le kamora kalafo ho bakuli ba nang le IAD e ka bonts'a phetoho ea ts'ebetso ea SG inhibition ea boko, phello ea kalafo mme ea ba sesupo sa ho bapisa mehato e fapaneng ea ho kenella e le ho lekola hore na ele li-electro- acupuncture ea sebetsa 'me u fumane mokhoa o sebetsang oa ho phekola. Thutong ena, re ile ra hira bakuli ba nang le IAD mme ra arola lithuto ka sehlopha sa electro-acupuncture (EA), sehlopha sa phallo ea kelello (PI) le sehlopha se felletseng sa kalafo (CT), re hlokometse phetoho ea matšoao a kelello le P50 ea AEP lihlopheng tsena tse tharo .

METHODA

Tekanyetso ea tlhahlobo

Tsebiso ea IA e entsoe ho latela maemo a amohelehang a fanoeng ke American Association of Psychology (1997).¹⁰

Mekhoa e kenyelelitsoeng

(A)

Mamello e matlafalitsoeng ea papali e bapaloang, ke hore, mokuli a ka khotsofatsoa ke feela ho hlakileng hore o bapala nako ea ho bapala; kapa o ne a sa khone ho felloa ke nako ea ho bapala net ka nako e sa fetoheng.

(B)

Ponahalo ea matšoao afe kapa afe a latelang ka mor'a ho emisa papali:

Matšoao a ho khaola ho bonahala: Matšoao a mabeli kapa ho feta a hlahile ka nako ea matsatsi a 'maloa kapa khoeli e le' ngoe ka mor'a hore mokuli a emise kapa a fokotse mokhoa o mobe oa ho bapala ka nako e telele, ho kenyelletsa: khatello ea maikutlo; psycho-motor irritability; ho nahana ka mokhoa o hlokolosi ka lintho tse etsahetseng nakong ea papali ea marang-rang; litoro kapa litoro ka lintho tse amanang le papali ea net-play; ka boithaopo kapa ka boithatelo liketso tsa dijithale tsa ho kokota ha keyboard. Matšoao ana a ka baka khatello ea maikutlo kapa litšitiso ho maemo a bophelo, mosebetsi kapa lintho tse ling tsa bohlokoa.

Tšaba ho sebelisa marang-rang kapa tšebeletso e ts'oanang le ena ho fokotsa kapa ho qoba matšoao a bang teng ha u khaotsa ho tsuba.

(C)

E bapalile inthanete khafetsa le ka nako e telele ho feta tekanyo e reriloeng.

(D)

Kamehla o ne a leka ho theola kapa ho thibela ho bapala papali ea chelete, empa liteko tsohle e ne e le tsa lefeela.

(E)

Ho qeta nako e ngata mesebetsing e amanang le inthanete, joalo ka ho reka libuka tse amanang le net, ho leka ho tsamaisa sebatli se secha le ho lahla thepa e jarollotsoeng.

(F)

Ka lebaka la papali e etsang chelete e ngata, mokuli o ile a behella ka thōko kapa a tlohela mesebetsi ea bohlokoa ea boithabiso, mosebetsi kapa boithabiso.

(G)

O ntse a tsoela pele ho bapala marang-rang a sa tsotelle, leha mokuli a ne a tseba mathata a phehellang kapa a etsahalang khafetsa a bakoang ke ho bapala 'mele, boiketlo ba batho, mosebetsi kapa kelello.

Mekhoa e ikhethang

Bakuli: (a) o ne a tšoeroe ke lefu la kelello ntle le IA; (b) o ne a e-na le nalane ea bokhoba ba lithethefatsi; (c) li ne li le khahlanong le sesupo sa EA, joalo ka mafu a pelo a matla, hematopathie, tumello e mpe, joalo-joalo; (d) e ne e le hypersensitive ho EA kapa e sa khone ho mamella ts'ebetso ea EA kapa ho akheha ho tsoa ho hlohlolong; le (e) bao e neng e le basali mme ba le baimana kapa ba anyang.

Boemo ba ho ithuta le litšobotsi tsa bongaka tsa barupeluoa

Kakaretso ea lithuto tse 120 tse keneng tekong ea bongaka ka ho fumana litlhahlobo tsa tsona li fihlella maemo a Internet Addiction (IA) li ile tsa hlahlojoa ho tsoa Sepetleleng sa Pele sa Teaching sa Chengdu University of Traditional Chinese Medicine, Tleliniking ea Ts'ebeliso ea Lithethefatsi ea Sepetlele sa Xiqu, Sepetlele se Akaretsang sa Sebaka sa Sesole sa Chengdu, le baithuti ba Xi'nan University of Finance le Economics le Chengdu TCM University. Kamora ho saena tokomane ea tumello e nang le tsebo, ba ile ba baloa ho latela tatellano ea ketelo ea bona mme ba abeloa lihlopha tse tharo ba sebelisa tafole ea dijithale e hlahisitsoeng ke software ea SAS 1 (mofuta oa 8.0 SAS Institute, Cary, NC, USA). Lihlooho tse mashome a mane li ile tsa abeloa sehlopha ka seng sa EA, sehlopha sa PI le sehlopha sa CT. Phuputso ena e entsoe ho latela melaoana ea Phatlalatso ea Helsinki (Edinburgh version, 8.0). Protocol ea ho ithuta e amohetsoe ke Komiti ea Boitšoaro ea Sepetlele sa 2000 sa Teaching sa Univesithi ea Chengdu ea Bongaka ba Setso ba China. Tumello e tsebisitsoeng e fumanoe ho bohle ba nkang karolo. Litšobotsi tsa bongaka tsa bankakarolo li bontšoa ho Lethathamo 1.

Tafole 1.

Litšobotsi tsa Clinical tsa barupeluoa ( x¯ ± s)

Lintlha: Sehlopha sa CT: se phekotsoe ka ho kenella ka kelellong le maikutlong a motlakase; Sehlopha sa EA: se phekotsoe feela ka electro-acupuncture; Sehlopha sa PI: se phekoloa feela ka ts'ebetso ea kelello. CT: Phekolo e felletseng; EA: electro-acupuncture; PI: Ho kenella hoa kelello.

Litlhahlobo tsa lipapali

Treatment

EA e ne e sebelisoa hanngoe ka letsatsi le leng le le leng bakeng sa 10 e latellanang e fetoha joalo ka thupelo e le 'ngoe, lithupelo tse peli li sebelisitsoe ka botlalo bakeng sa nyeoe ka' ngoe. Likhetho tsa Acupoints: Baihui (GV 20), Sishengcong (EX-HN 1), Hegu (LI 4), Neiguan (PC 6), Taichong (LR 3) le Sanyinjiao (SP 6). Ts'ebetso: Bakuli ba maemong a phahameng. Huatuo brand 0.25 mm × 40 / 25 limilone tse se nang mabone tse tsoang Company Suzg Medical Equipment Company (Suzhou, China) li ile tsa sebelisoa, tsa kenngoa ka mokhoa o tloaelehileng, tsa sebelisa mokhoa o tšoanang oa ho matlafatsa ho fihlela “De Qi”. Ho ne ho bolokiloe linalete Baihui (GV 20), Neiguan (PC 6) le Sanyinjiao (SP 6) bakeng sa metsotso e ka bang 30 mme li fuoe nalete-e sebelisang metsotso e meng le e meng e 10; sehlopha sa ts'usumetso ea motlakase se sebelisitsoe ho para e le 'ngoe ea li-acupoints tsa 4 tsa Sishengcong (EX-HN 1), ho sebelisoa lintlha tsa ho le letona / leqeleng le lintlha tse kaholimo / tse tlase ka ho fapana; sehlopha se seng sa ts'usumetso ea motlakase se sebelisitsoe ho Hegu (LI 4) le Taichong (LR 3), ho sebelisoa li-acupoints ka lehlakoreng le letona le ka leqeleng ka ho fapana. Seo se bolela hore lihlopha tse peli tsa ts'usumetso li sebelisitsoe ho li-acupoints tsa 4 (lipara tse 2) molemong oa kalafo ea EA. Tsosoloso ea motlakase e ne e sebelisoa ho sebelisoa sesebelisoa sa li-electro-acupuncture sa mefuta e mengata ea G6805 se tsoang Huayi Factory sesebelisoa sa bongaka (Shanghai, China), se nang le mekhahlelo e behiloeng ea maqhubu a 10-100 Hz, leqhubu le fokolang haholo, bophara ba 0.3 ms, matla ea ts'usumetso e ne e behiloe ho latela mamello ea mokuli mme e bolokiloe metsotso e 30.

PI e sebelisitsoe ka mokhoa oa boits'oaro ba boits'oaro ho 4: 00-5: 00 PM matsatsing a mang le a mang a 4, ka 30 min nako e ngoe le e ngoe, ka makhetlo a 5 e le thupelo e le 'ngoe,' me lithuto tse peli li sebelisitsoe. E tsoetse pele lintlheng tse 4: (a) Ho tloaelana le liphihlelo tsa mokuli tsa pele, le ho tseba metso ea sebōpeho sa hae se fosahetseng le maikutlo a mabe; (b) ho lekanya marang-rang ka sepheo se hlakileng le se hlakileng hammoho le mokuli ho fetola likarolo tsa hae tsa kutloisiso ea ho nkeha maikutlo le ho itšetleha ka eena; (c) ho theha kemiso ea ts'ebetso ea mosebetsi / phomolo hammoho le mokuli, ho khutlisa bophelo ba hae bo hlophisehileng; le (d) ho matlafatsa boits'oaro ka ho buisana le ho ingolisa tumellanong ea IA ea ho ithiba hammoho le mokuli le litho tsa lelapa la hae bakeng sa ho fokotsa IA butle-butle. Ka sehlopha se akaretsang sa kalafo (CT), EA plus PI e ile ea fanoa, ka EA bakeng sa makhetlo a 10 le PI bakeng sa 5 e fetoha thupelo e le 'ngoe.

Tekanyo

Maemo a kliniki a bakuli a ne a hlohlelletsoa ka ho beha lintlha ho sebelisa tekanyo ea ho ikala bakeng sa IAD le SCL-90. The lintlha li nkuoe makhetlo a 2 ka tatellano qalong le qetellong ea nyeoe, 'me liphetho tsa rekota. Tekanyetso ea IAD e thehiloe ke Kimberly Young, Univesithi ea Pittsburgh, USA.¹¹

SCL-90 e na le lintho tsa 90, 'me e arotsoe ka mekhahlelo ea 5 ka ho beha 1-5.¹² Lipalo tse felletseng le matšoao a tloaelehileng a lintho tse ntle hammoho le lintlha tse ngata ho kenyelletsa matšoao a somatization, matšoao a ho qobella ho qhekella, maikutlo a ho ikopanya le batho, khatello ea maikutlo, ho tšoenyeha, ho hlekefetsoa le ho tšabeha, matšoao a paranoid, a psychotic a ile a hlahlojoa.

Liqeto tsohle li ne li sebelisoa tlasa taelo ea mohlahlobi, sebakeng se khutsitseng, testee ka mokhoa o hlakileng le tsepamiso ea hae e tsepamisitsoeng. Tlhatlhobo e ile ea phethoa ke tekhenoloji e khethehileng e khethiloeng.

Ho shebella ho ERP ho entsoe 9: 00-12: 00 ke kamoreng e sirelelitsoeng, e amohelang mokhoa oa Su et al, ¹³ o sebelisa MEB 9200-e tsitsitseng lehloekisi le ka hlahisang Khampani ea Nihon Kohden (Tokyo, Japan). Lipuo tse kopaneng tsa lipuo tse kopaneng le liteko tsa liteko li ile tsa lateloa nakong ea tlhahlobo, mme ts'ebetso e entsoe ke motho ea rarollotsoeng.

Ho latela mokhoa oa machabeng oa 10/20 oa sistimi ea electroencephalogram, li-electrode tsa ho rekota li ile tsa beoa ntlheng ea hlooho ea hlooho (Cz) le bohareng ba phatla le lefatše le hokahane; li-electrode tsa litšupiso tse fumanehang lintlheng tse kopaneng, khoelehetso e behiloeng lipakeng tsa eleketrode le letlalo ho <5 kΩ. Ho penya habeli (S1, S2) ho hlahisitsoe ke jenereithara ea lets'oao le kantle e nang le makhetlo a 85Hz. Ho tobetsa ho ne ho le maqhubu a maqhubu a maqhubu le li-0.10ms ka nako e telele. Teko ka 'ngoe e ne e e-na le ho penya habeli (S1, S2) ka karohano ea li-500ms. Liteko li ile tsa phetoa kahare ho li-10. Bafo ba ile ba fuoa lihlopha tsa 32 tsa li-stimulus tse peli ka li-headphone. Litšusumetso tsa S1 le S2 li ile tsa etsoa sampole ka tatellano le ka tatellano. Letšoao la ho kenya le ile la eketsoa 200ms ho hlahloba fensetere. P50 e ntšitsoeng ke S1 e ne e le conditioning (S1-P50) ha S2 e ntse e leka (S2-P50). Botsitso le bophahamo ba S1-P50 le S2-P50 hammoho le karo-karolelano ea molumo oa S2-P50 le S1-P50 (S2 / S1), le phapang lipakeng tsa molumo oa S1-P50 le S2-P50 (S1- S2) li ngotsoe.

Tlhahlobo ea Litekanyetso

Lintlha li ile tsa hlahisoa e le ho kheloha ho tloaelehileng (( x¯ ± s), hape e hlahlobiloe ka SPSS 13.0 (mofuta oa 13.0 SPSS Inc., Chicago, IL, USA), T-Test, tlhahlobo e le 'ngoe ea phapang e fapaneng, χ² tlhahlobo, Teko ea Ridit e ile ea etsoa ho leka liphapang lipakeng tsa lihlopha. P <0.05 e ne e nkuoa e le ea bohlokoa ka lipalo.

LIPOTSO

Palo ea lithuto tsa 112 ka kakaretso e fihletse tlhahlobo ea ho qetela ea nyeoe (Setšoantšo sa 1). Lithuto tse robeli li ile tsa tsoa: sehlooho se le seng sehlopheng sa EA se ile sa tsoa ka lebaka la ho akheha nakong ea kalafo ea EA ea pele; har'a lithuto tse 'ne sehlopheng sa PI, e mong o ile a tsoa ka lebaka la kalafo ea pelo e matla ka mor'a kalafo ea PI e' meli, tse peli ka lebaka la tlhahlobo ea sekolo pele ho kalafo ea 4th PI, 'me ea ho qetela ka lebaka la tlhoko ea ho etela nkhono oa hae ea kulang haholo kamora' 4th PI kalafo; har'a lithuto tse tharo sehlopheng sa CT, e le 'ngoe e ile ea theoha kamora kalafo ea pele bakeng sa kamohelo ea kantle ho toropo, tse peli ho ea ngola tlhahlobo ka mor'a 1st le 3rd CT, ka ho latellana.

Setšoantšo sa 1. 

Setšoantšo sa flow sa barupeluoa

Sehlopha sa CT: se alafshoa ka ho kenella maikutlong le kelellong; Sehlopha sa EA: se phekotsoe feela ka electro-acupuncture; Sehlopha sa PI: se phekoloa feela ka ts'ebetso ea kelello. CT: Phekolo e felletseng; EA: electro-acupuncture; PI: Ho kenella hoa kelello.

Mokhoa oa ho khetha

Papiso ea IA Scores

Lipalo tsa IA pele ho kalafo lihlopheng tsena tse tharo li ne li fapane haholo (P > 0.05). Kamora kalafo, lintlha li ile tsa fokotseha lihlopheng tsohle tse tharo (P <0.05), mme degree ea IA e ba nkile e le CT <EA <PI (all P <0.05, Lethathamo 2).

Tafole 2.

Ho bapisoa ha IA tse ngata tsa lihlopha tsa PI, EA, CT ( x¯ ± s)

Lintlha: Sehlopha sa CT: se phekotsoe ka ho kenella ka kelellong le maikutlong a motlakase; Sehlopha sa EA: se phekotsoe feela ka electro-acupuncture; Sehlopha sa PI: se phekoloa feela ka ts'ebetso ea kelello. CT: Phekolo e felletseng; EA: electro-acupuncture; PI: Ho kenella hoa kelello.

a

P <0.05, ha e bapisoa le pele ho kalafo;

b

P <0.05, ha e bapisoa le sehlopha sa PI;

c

P <0.05, ha e bapisoa le sehlopha sa EA.

Litlhahlobo tsa lipapali

Ho bapisoa ha ScL-90 Scores

Kamora kalafo, lintlha tsohle tsa SCL-90 le lintlha tsohle li fokotsehile haholo (P <0.05); sehlopheng sa EA, ntle le lebaka la bora le tšabo, lipalo kaofela le lintlha tse ling li fokotsehile haholo (P <0.05); sehlopheng sa PI, ntle le bongata ba somatization le tšabo, lintlha le lintlha tse ling kaofela li fokotsehile haholo. Lintlha tse felletseng le matšoao a karolelano ea lintho tse ntle hammoho le lintlha tse ngata tse kenyeletsang matšoao a ho iketelletsa pele, matšoao a qobelloang a ho qobelloa, kutloisiso ea batho, khatello ea maikutlo, ho tšoenyeha, bora le ho tšabehang, matšoao a kelello, matšoao a kelello le lintlha tse ling sehlopheng sa CT li ne li le bohlokoa haholo. tlase ho sehlopha sa EA le PI (P <0.05). Lintlha tse felletseng le lintlha tsohle tsa sehlopha sa EA li ne li fapane hole le tsa sehlopha sa PI (P <0.05, Lethathamo 3).

Tafole 3.

Ho bapisoa ha lintlha tsa SCL-90 tsa PI, EA, lihlopha tsa CT ( x¯ ± s)

Lintlha: Sehlopha sa CT: se phekotsoe ka ho kenella ka kelellong le maikutlong a motlakase; Sehlopha sa EA: se phekotsoe feela ka electro-acupuncture; Sehlopha sa PI: se phekoloa feela ka ts'ebetso ea kelello. CT: Phekolo e felletseng; EA: electro-acupuncture; PI: Ho kenella hoa kelello.

a

P <0.05, ha e bapisoa le kalafo ea pele ho nako;

b

P <0.05, ha e bapisoa le sehlopha sa PI;

c

P <0.05, ha e bapisoa le sehlopha sa EA.

Litlhahlobo tsa lipapali

Ho bapisoa ha Latency le Amplitude ea P50

Kamora kalafo, latency ea S1-P50 sehlopheng sa PI le S2-P50 sehlopheng sa CT e ile ea eketseha haholo (P <0.05). Latency ea S1-P50 sehlopheng sa CT e fokotsoe haholo ho feta ea sehlopha sa PI le sehlopha sa EA (P <0.05). Phapang lipakeng tsa boholo ba S1-P50 le S2-P50 (S1-S2) e eketsehile haholo (P <0.05). S1-S2 sehlopheng sa EA le eona e ne e phahame ho feta pele empa e bile le phapang e sa reng letho (P > 0.05, Lethathamo 4 ;  Lethathamo 5).

Tafole 4.

Ho bapisoa ha latency ea P50 ea PI, EA, lihlopha tsa CT (ms, x¯ ± s)

Lintlha: Sehlopha sa CT: se phekotsoe ka ho kenella ka kelellong le maikutlong a motlakase; Sehlopha sa EA: se phekotsoe feela ka electro-acupuncture; Sehlopha sa PI: se phekoloa feela ka ts'ebetso ea kelello. CT: Phekolo e felletseng; EA: electro-acupuncture; PI: Ho kenella hoa kelello.

a

P <0.05, ha e bapisoa le kalafo ea pele ho nako;

b

P <0.05, ha e bapisoa le sehlopha sa PI;

c

P <0.05, ha e bapisoa le sehlopha sa EA.

Litlhahlobo tsa lipapali

Tafole 5.

Ho bapisoa ha amplitude ea P50 ea PI, EA, lihlopha tsa CT (μV, x¯ ± s)

Lintlha: Sehlopha sa CT: se phekotsoe ka ho kenella ka kelellong le maikutlong a motlakase; Sehlopha sa EA: se phekotsoe feela ka electro-acupuncture; Sehlopha sa PI: se phekoloa feela ka ts'ebetso ea kelello. CT: Phekolo e felletseng; EA: electro-acupuncture; PI: Ho kenella hoa kelello.

a

P <0.05, ha e bapisoa le kalafo ea pele ho nako.

Litlhahlobo tsa lipapali

TŠOHLOA

Thutong ena, liphetho tsa sekala sa ho itlhahloba bakeng sa IAD phuputsong ena li bontšitse hore kamora kalafo lintlha tsa IAD li fokotsehile haholo. Lintlha sehlopheng sa CT li ne li le tlase haholo ho feta sehlopheng sa EA le PI. Ke ho re, kalafo e felletseng (EA + PI) e ka ba le phello e kholo ho phekoleng IAD.

SCL-90 e ka bonahatsa ka botlalo matšoao a Psychological a bankakarolo ka ho sekaseka mohopolo, maikutlo, ho nahana, tsebo, boitšoaro le mokhoa oa bophelo, kamano ea motho, lijo le boroko, jj. Ho ka tseba hore na batho ba bohlasong ba kelello kapa eseng.^{14; 15 ;  16} Thutong ena, kamora CT, palo eohle le lintlha tsohle tsa SCL-90 li fokotsehile haholo (P <0.05); le lintlha tse felletseng le matšoao a karolelano ea lintho tse ntle hammoho le lintlha tse ngata tse kenyeletsang matšoao a qobelloang a khatello ea maikutlo, khatello ea maikutlo, matšoenyeho, matšoao a psychotic le lintlha tse ling sehlopheng sa CT li ne li le tlase haholo ho feta sehlopheng sa EA le PI. Sephetho se bonts'itse hore CT e ka laola maemo a kelello le ho ntlafatsa boemo ba bophelo bo botle ba kelello.

Sensory gating (SG) e bolela thepa ea kelello ho khutlisa mohopolo o sa amaneng le maikutlo. Thepa ea mofuta ona e amana haufi le tataiso ea mosebetsi oa kelello. Boko bo ka thibela ts'usumetso e sa amaneng le SG e le hore e se ke ea susumetsoa haholo. Ho haelloa ke SG ho ka baka mathata a mangata a kelello haholo-holo likotsi tsa tlhokomelo.¹⁷ AEP P50, e liehang ho thusa molemong oa bokhoni ba ho tsosoa, hangata e hlaha e le 30∼90ms kamora ho hlohlelletsa, e le ntlha ea tlhaiso ea motlakase ea motlakase e bonts'ang SG. Ha lithuto li fumana khothatso e phetoang khafetsa ka linako tse khuts'oane, ho eketseha ha AEP P50 ho ne ho tla fokotseha. Mofuta oa mofuta oo oa ponaletso ke bokhoni ba boinotšing ba ho itšireletsa ba ho tlosa tšusumetso e sa amaneng le eona. Karolelano ea amplitude ea S2-P50 le S1-P50 (S2 / S1), le phapang lipakeng tsa amplitude ea S1-P50 le S2-P50 (S1-S2) e ka bonts'a ts'ebetso ea mantlha ea boko.^{18 ;  19} Karolelano e nyane ea S2 / S1, kapa phapang e kholo ea S1-S2, mosebetsi o matla oa SG.

Ho bonts'itsoe thutong ena hore kamora CT phapang lipakeng tsa amplitude ea S1P50 le S2P50 (S1-S2) e ile ea eketseha haholo, e fana ka maikutlo a hore CT e ka fokotsa matšoao a kelello a bakuli ka ho laola ts'ebetso ea SG le ho fokotsa khatello e matla e sa amaneng.

Qetellong, thuto e netefalitse hore CT e ka fokotsa matšoao a kelello a bakuli ba IAD, mme mochine o ka amana le litlamorao tsa ona ho ntlafatsa tšebetso ea methapo ea kutlo ea boko ho bakuli ba IAD.

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E tšehetsoa keMotheo oa Naha oa Saense oa Tlhaho oa China: Patlisiso ea Mechanism e Bohareng ka Tlhaho ea Electro ho Hloekisa Khanyetso ea Marang-rang ea Bakuli ba nang le Ts'ebeliso ea Marang-rang ea Pathological e thehiloeng ho Sistimi ea Mirror Neuron(Che. 81574047); Patlisiso ea Mokhoa o Bohareng oa Mokhoa oa ho Arabela ka Tlhokahalo ea Electro ho Phokotso ea Tlhatlhobo ea Taolo ea Tlatsetso ea Ts'ebeliso ea Inthanete.(Che. 81072852); Letlole la Fok Ying Tung Education Foundation: Patlisiso ea Mechanism ea Kopano e Akaretsang mabapi le Tlhahlobo ea Electro mabapi le Tlhabollo ea Liphetoho tsa Taolo ea Pele ea Cortex-Buckle.(Che. 131106); Lichelete tsa Koetliso tsa Moetapele oa Boithuto le Setsebi Profinseng ea Sichuan: Patlisiso mabapi le Mechanism e Bohareng ea Tlhabollo ea Tlatsetso ea Electro-Acupuncture bakeng sa Tlatsetso ea Tlatsetso ea Marang-rang e Thehiloeng ho Network Memory Working Memory Network; Ho sebelisoa li-Projeke tsa Boithuto ba mantlha ba Lefapha la Saense le Theknoloji ea Sichuan: Patlisiso ea Mechanism ea Kopano e Akaretsang mabapi le Phello ea Electro Acupuncture mabapi le Brain Working Memory ea Bakuli ba Lemaletseng Keketseho ea Inthanete.(Che. 2013JY0162); Morero oa Lefapha la Bophelo bo Botle la Sichuan: Patlisiso ka Bokhoni ba ho Sebetsa ba Brain le Litšobotsi tsa Electroencephalograph Entropy ho Bakuli ba IAD(Che. 110083); Morero oa Tlhatlhobo ea Theknoloji ea Batho le Ntšetso-pele ea Chengdu Saense le Theknoloji ea Chengdu: Patlisiso ka Electro Acupuncture ho 5-HT le 5-HTT Gene hammoho le Phatlalatso ea Ts'ebeliso ea Bakuli ba Pathological Internet Use.(Che. 2014-HM01-00180-SF); Morero oa morero oa phetoho ea lithuto tsa koleche le lithuto tsa lithuto tsa lithuto tsa lithuto tsa lithuto le litsi tsa thuto ea lithuto tsa univesithi le liunivesithi tsa Chengdu: Patlisiso ea Mechanism e Bohareng ea Boikarabello le Kameho ea Tlhatlhobo ea Electro mabapi le Bakuli ba Memelang Bakuli ba IAD.(Che. 12DXYB148JH-002)

Litaba tse mabapi le: Prof. Zhu Tianmin, K'holejeng ea Thupelo ea 'mele le ho ikoetlisa, Chengdu University of Medical China Chinese Chengdu 610075, China, Telephone: + 86-13608216905

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