Prog Neuropsychopharmacol Biol Psychiatry. 2019 Jun 27: 109680. Doi: 10.1016 / j.pnpbp.2019.109680.
Kim H1, Kim YK2, Lee JY3, Choi AR3, Kim DJ4, Choi JS5.
inahaneloang
Bothata ba lipapali tsa inthanete (IGD) e fetohile taba ea ho tšoenyeha ho hoholo e le mokhoa o lemalloang 'me o bapisoa le ts'ebeliso ea lithethefatsi / e seng e amanang le lithethefatsi. Le ha IGD e bonts'a ho senyeha ha bongaka le ho se sebetse hantle sechabeng, liphetoho tse amanang le neurobiological ho IGD ha li so hlakisoe hantle. Re ne re tloaetse 18F-fluorodeoxyglucose PET ho fuputsa phapang lipakeng tsa glucose metabolism le kgokahano ea metabolic ho banna ba banyane [bakuli ba mashome a mararo a metso e ts'eletseng ba nang le IGD, bakuli ba mashome a mabeli a metso e ts'eletseng ba nang le tahi ea tšebeliso ea joala (AUD) le li-control tse mashome a mararo a metso e robong tse nang le taolo (HC). Ha e bapisoa le HC, IGD e bontsitse hypometabolism ho anterior cingrate cortex (ACC), temporal, frontal, parietal le striatum mme AUD e bonts'itse hypometabolism ho occipital, temporali le parietal lobule. Ho feta moo, IGD e bontšitse khokahano e mpe lipakeng tsa ACC le nako ea papali le lipakeng tsa cortex ea orbitofrontal le impulsivity. Hape, IGD e ne e na le tšebelisano e tlase ea metabolic pakeng tsa libaka tsa nakoana le tsa maoto le lipakeng tsa sebaka sa makoloi le sebaka sa occipital. 'Me AUD e bontšitse khokahano e kholo ea metabolic pakeng tsa libaka tsa orbitof Pambal le tsa parietal, le lipakeng tsa somatosensory kapa parietal le temporal, empa ho hokahana ka tlase ho metabolic libakeng tsa Fronto-striatal kapa Fronto-limbic. Liphetho tsa rona li fana ka bopaki ba hore ts'ebetso ea hypometabolism le khokahano e fetotsoeng ea metabolism ho IGD e kanna ea amana le ts'ebetso e sa tloaelehang ea mehopolo ea maikutlo ka lipapali tsa nako e telele tsa lipapali le ho se sebetse ha linaha tse susumetsang / tse susumetsang.
LINKOTSO: Bothata ba tšebeliso ea joala; Glucose metabolism; Bothata ba lipapali tsa inthanete; Khokahano ea Metabolic; Positron emission tomography
PMID: 31255649
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