Psychoneuroendocrinology. Kajeno Jan 2017; 10: 77-244. doi: 251 / j.psyneuen.10.1016.
Kaess M1, Parzer P2, Mehl L3, Mofuthu L3, Strittmatter E4, Pheta F2, Koenig J3.
inahaneloang
Mathata a Lipapali a Marang-rang [IGD] a ile a hlahisoa e le bokhoba bo bocha ba boits'oaro ho DSM-5 Karolo ea 3. Ho ba tlokotsing ea khatello ea maikutlo ke lebaka le ka bakang IGD. Ka lebaka la ho haella ha tlhaiso-leseling e neng e le teng pele, thuto e ile ea batlisisa liphapang tsa karabelo ea kelello le neurobiological ho khatello ea maikutlo e matla ho bakuli ba nang le IGD. Bahlankana ba 24 (lilemo tse bolelang lilemo tse 18.38; lilemo tse 13-25) ba phethahatsang litekanyetso tsa DSM-5 tsa IGD le 25 tse tsamaisanang le taolo ba ile ba etsa tlhahlobo ea Trier Social Stress Test [TSST]. Barupeluoa ba fane ka mehlala ea moriri bakeng sa tlhahlobo ea ts'ebetso ea axal hypothalamic-pituitary-adrenal [HPA] le lipuisano tsa bongaka li ile tsa etsoa ho lekola psychopathology. Nakong ea liteko, barupeluoa ba ile ba tlaleha ka boiphihlelo ba bona ba khatello ea maikutlo le litlamorao tsa motsotsoana, ha feela mehlala ea cortisol ea mathe le sekhahla sa lipelo tsa bona se ile sa hatisoa khafetsa. Bakuli ba nang le IGD ba tlaleha khatello e kholo ea letsatsi le letsatsi le e sa foleng, hammoho le comorbidity ea psychopathological. Ha ho phapang e fumanoeng ka mehato ea moriri oa cortisol. Ha li bapisoa le taolo, bakuli ba IGD ba bontšitse karabelo e fokolitsoeng ea cortisol (χ2(7)= 25.75, p <0.001) le litlamorao tse mpe tse mpe (χ2(7)= 17.25, p = 0.016) ho arabela khatello ea maikutlo e matla. Ho otla ha pelo (χ2(1)= 5.49, p = 0.019), litlamorao tse mpe (χ2(1)= 5.60, p = 0.018) le khatello ea maikutlo (χ2(1)= 5.55, p = 0.019) li ile tsa eketseha hanyane ka hanyane ho bakuli ba IGD. Kamora ho ikamahanya le mesebetsi ea lipapali, bakuli ba IGD ba bontšitse ho fokotseha ha nakoana ha cortisol (χ2(1)= 5.20, p = 0.022), e ka bonts'ang ts'ebetso e akaretsang ea HPA-axis ho feta phetoho e nchafalitsoeng. Ho sebetsana le khatello ea maikutlo ho bonts'a likamano le ho tiea ha matšoao a IGD. Liphuputso li bonts'a liphapang tsa khatello e matla ea kelello le methapo ea kutlo ho bakuli ba nang le IGD. Liphetoho tsa sistimi ea khatello ea maikutlo li ka nka karolo ho nts'etsopele le tlhokomelo ea IGD.
LITLHAKU TSE KHOLO: Ho lemalla boitšoaro; Cortisol; Ho otla ha pelo; Mathata a ho bapala Inthaneteng; Khatello ea maikutlo; Teko ea khatello ea maikutlo ea sechaba
PMID: 28122298
DOI: 10.1016 / j.psyneuen.2017.01.008
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