Striatum morphometry e amahanngoa le bothata ba ho laola maikutlo le ho ba le matšoao a matšoao bothateng ba ho bapala Inthaneteng (2015))

Mathata a lipapali tsa inthanete (IGD), a fumanoeng khatisong ea bohlano ea Diagnostic and Statistical Manual of Mental Disorders (DSM-V) Karolo ea III e le boemo bo lumellang lipatlisiso tse ling tsa bongaka, e kanna ea amahanngoa le taolo e senyehileng ea kutloisiso. Liphuputso tse fetileng tse amanang le IGD li ne li senotse ho se ts'oanehe hoa sebopeho sa preortal cortex, karolo ea bohlokoa ea lipotoloho tsa pele ho nako, tse bapalang karolo ea bohlokoa taolong ea kutloisiso. Leha ho le joalo, ha ho tsejoe hanyane ka kamano lipakeng tsa striatal nuclei (caudate, putamen, and nucleus accumbens) meqolo le tlhaiso ea taolo ea kelello ho batho ba nang le IGD. Bacha ba mashome a mabeli a metso e supileng ba nang le IGD le lilemo tse 30-, tekano- le taolo e tsamaellanang le thuto ba nkile karolo thutong ena. Phapang ea molumo oa striatum e ile ea lekoa ka ho lekanya bophahamo ba subcortical ho FreeSurfer. Khabareng, mosebetsi oa Stroop o ne o sebelisetsoa ho bona likhaello tsa taolo ea kelello. Tlhatlhobo ea Correlation e sebelisitsoe ho etsa lipatlisiso ka kamano lipakeng tsa meqolo ea pelehi le ts'ebetso mosebetsing oa Stroop hammoho le ho tiea ha IGD. Mabapi le taolo, IGD e entse liphoso tse ngata tse sa sebetseng nakong ea mosebetsi oa Stroop mme ea bonts'a palo e eketsehileng ea dorsal striatum (caudate) le ventral striatum (nucleus accumbens). Ntle le moo, bophahamo ba modumo bo ne bo amahanngoa le ts'ebetso ea Stroop task performance le li-nucleus accumbens (NAc) li ne li amahanngoa le sekhahla sa inthanete sa lithethefatsi (IAT) sehlopheng sa IGD. Mefuta e eketsehileng ea caudate e nepahetseng le NAc le kamano ea bona le litšobotsi tsa boits'oaro (ke hore, taolo ea kutloisiso le ho tiea) ho IGD li fumanoe thutong ea hajoale. Liphuputso tsa rona li fana ka maikutlo a hore striatum e kanna ea ameha ho pathophysiology ea mantlha ea IGD.