J Motlatsi oa Med. 2012 Jun 20.
Montag C, Kirsch P, Sauer C, Markett S, Reuter M.
mohloli o moholo
Ho tsoa Lefapheng la Psychology (CM, SM, MR), Laboratori ea Neurogenetics (CM, SM, MR), le Setsi sa Economics & Neuroscience (CM, SMM, MR), University of Bonn, Bonn, Germany; le Lefapha la Clinical Psychology (PK, CS), Central Institute of Mental Health, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany.
inahaneloang
Boithuto ba morao-rao bo tsoang Asia bo fane ka bopaki ba pele bakeng sa khokahano ea liphatsa tsa lefutso pakeng tsa serotonergic le dopaminergic neurotransmission le ho lemalla tahi ea inthanete. Tlaleho ea hona joale e fana ka datha ka mofuta o mocha oa mokhethoa lipatlisisong tsa ts'ebeliso ea litheko tsa inthanete-mofuta oa mofuta oa nicotinic acetylcholine receptor subunit alpha 4 (CHRNA4). Ho ile ha etsoa thuto ea taolo ea linyeoe. Barupeluoa ba ile ba khethoa ho tsoa bankeng e kholo ea tlhaiso-leseling, ho kenyelletsoa le batho ba akaretsang le ba tsoang yunivesithi. Kakaretso ea barupeluoa ba 132 ba sebelisang mathata a Marang-rang le mathata a lilemo tsa 132- le taolo e amanang le thobalano ba nkile karolo ho ithuteng. Barupeluoa ba ile ba fana ka mehlala ea DNA mme ba tlatsa lethathamong la tlhahlobo ea litheko tsa inthanete. T-variant (CC genotype) ea polymorphism ea rs1044396 ho genR CHXNA4 e hlahile hangata haholo sehlopheng sa linyeoe. Patlisiso e 'ngoe e bontšitse hore phello ena e ne e tsamaisoa ke basali. Ha e kopantsoe le liphumano tse tsoang liphuputsong tse ling, lintlha tsa hona joale tsa data moo tataiso e tsoang teng ke hore naX1044396 e fana ka litlamorao tse ngata boits'oarong, ho kenyeletsoa temohisiso, maikutlo le bokhoba.
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