TLHOKOMELISO: Mehopolo ea bokhoba ba tlhekefetso le taolo ea litšusumetso e fetoha ha ho bonahatsoa ho tse 11th mofuta oa International Classization of Dis shida (ICD-11, WHO, 2018). Leha ho le joalo, lithuto tse shebaneng le phapano e tobileng ea phapang ea sebopeho sa bokhoba ba litekanyetso tsa boitšoaro le lithethefatsi li lekantsoe.
SEBELE: Mona re bapisa litaba tsa bohloeki (GMVs) ho lihlopha tsohle tsa batho ba nang le ts'oaetso ea tlhekefetso ea thobalano (CSBD), bothata ba papali ea chelete (GD), le bothata ba tšebeliso ea joala (AUD) le ba se nang mathata ana (barupeluoa ba laolehileng ba phetseng hantle; HCs).
MANEHELO: Voxel-based morphometry (VBM) e ne e hiriloe ho ithuta sebopeho sa boko le ho bonahatsa matšoao a tlhekefetso ho hlahlojoang ka lipotso. Ho khetholla libaka tsa boko tse amanang le ho teba ha litumelo, likhokahano lipakeng tsa lintlha tsa lipotso le li-GMV li ile tsa thathamisoa.
MAIN OUTCOME: Re bokelletse data ea MRI (GMVs) ho bakuli ba 26 ba CSBD, bakuli ba 26 GD, bakuli ba 21 ba AUD le barupeluoa ba 25 HC (banna bohle ba bong bo fapaneng; lilemo: 24-60; M = 34.5, SD = 6.48).
LITLHAKISO: Batho ba amehileng (CSBD, GD, AUD) ha ba bapisoa le barupeluoa ba HC ba bonts'itse li-GMV tse nyane holima lepolanka le kapele, ka kotloloho ho orbitof Pambal cortex. Phapang e neng e buuoa haholo e ile ea bonoa lihlopheng tsa GD le AUD, le bonyane sehlopheng sa CSBD. Ho bile le khokahano e mpe pakeng tsa li-GMV le bokhopo bo tebileng sehlopheng sa CSBD. Bophahamo bo phahameng ba matšoao a CSBD bo ile ba lumellana le ho fokotseha ha GMV ho "anterior" cingrate gyrus e nepahetseng.
LITLHAHISO TSA MOKHOA: Seo re se fumaneng se fana ka maikutlo a tšoanang lipakeng tsa taolo e itseng ea taolo ea tšusumetso le litlamorao.
LITLHAKISO LE LITLHAKISO: Thutong ena ke ea pele e bonts'ang li-GMV tse nyane lihlopheng tse 3 tsa bongaka tsa CSBD, GD le AUD. Empa thuto e ne e lekanyetsoa feela ho banna ba bong bo fapaneng. Boithuto ba nako e telele bo lokela ho lekola hore na ho theoha ha molumo oa moea pele ho nako ho ka emela lintlha tse pepesitsoeng kapa hore na li ka ba teng ka ho eketseha ha boteng.
CONCLUSIONS: Patlisiso ea rona e fetisa liphumano tsa pele ho mathata a ts'ebeliso ea lithethefatsi a GMV e tlase maemong a mantlha a bakuli ba nang le taolo e itseng ea tšusumetso le mathata a boitšoaro le lithethefatsi. Kamano e mpe pakeng tsa li-GMV le matšoao a CSBD le anterior cingrate gyrus e fana ka khokahano le matšoao a kliniki.
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