Psychoneuroendocrinology. 2015 Nov; 61: 53. Doi: 10.1016 / j.psyneuen.2015.07.534. Epub 2015 Aug 8.
Chatzittofis A1, Arver S1, Öberg K1, Hallberg J1, Nordström P1, Jokinen J.
Lintlha-khōlō Tsa
- Banna ba nang le bothata ba khatello ea maikutlo bo ne bo le boholo bo phahameng ba khatello ea DST ntle le khatello.
- Banna ba nang le bothata ba hypersexual ba ne ba e-na le maemo a phahameng a DST-ACTH ha a bapisoa le taolo.
inahaneloang
Hypersexual disorder e kopanyang likarolo tsa pathophysiological tse kang ho khaotsa takatso ea thobalano, bokhoba ba thobalano, ho ts'oaroa le ho qobelloa ho ile ha khothalletsoa e le tlhahlobo ea DSM-5. Leha ho le joalo, ha ho tsejoe hanyane ka neurobiology e bakang lefu lena. Ho hlahlojoa ha hypothalamic pituitary adrenal (HPA) axis ho bontšitsoe mathateng a kelello empa ha ho so ka ho fuputsoa moferefere oa hypersexual. Morero oa thuto ena e ne e le ho etsa lipatlisiso mabapi le ts'ebetso ea axero ea HPA ho hypersexual disc.
Boithuto bona bo kenyelletsa bakuli ba banna ba 67 ba nang le hypersexual disc le baithaopi ba phetseng hantle ba 39. Litekanyetso tsa basal tsa hoseng tsa plasma tsa cortisol le ACTH li ile tsa hlahlojoa mme tlhahlobo ea khatello e tlase ea (0.5 mg) dexamethasone e ile ea etsoa ka cortisol le ACTH e lekantsoeng ea post dexamethasone. Boemo bo sa hatelloeng bo ne bo hlalosoa ka maemo a DST-cortisol ≥138 nmol / l. Sekala sa tlhahlobo ea khatello ea thobalano (SCS), Hypersexual disorder (HD: CAS), Montgomery-Åsberg Depression Scale-self rating (MADRS-S) le lipotso tsa bana ba ngoana ea lilemong tsa bocha (CTQ), li ile tsa sebelisoa ho lekola boitšoaro ba khatello ea maikutlo, khatello ea maikutlo le khatello ea maikutlo litsietsi tsa pele bophelong.
Bakuli ba nang le lefu la ho ferekana kelellong ba ne ba atisa ho ba le li-suppress tse se nang khatello ea DST haholo mme ba bile le maemo a phahameng haholo a DST-ACTH ha a bapisoa le baithaopi ba phetseng hantle. Bakuli ba tlaleha ho sithabela ha bana le matšoao a khatello ea maikutlo ha ba bapisoa le baithaopi ba phetseng hantle. Likolo tsa CTQ li bonts'itse kamano e mpe e amanang le DST-ACTH athe SCS le HD: Likolo tsa CAS li bontšitse khokahano e mpe le basement cortisol ho bakuli. Ho fumanoa ha lefu la hypersexual ho ne ho amana haholo le DST eseng khatello le plasma e phahameng ea DST-ACTH leha e ne e lokisoa bakeng sa ho sithabela maikutlong bongoaneng.
Liphetho li bontša ho hlohlona ha axis ho HPA ho bakuli ba banna ba nang le khatello ea maikutlo.
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