Boleng ba moputso bo ikhethileng ba takatso ea thobalano bo bontšitsoe ho criex ea motho le orbitofrontal cortex (2020)

Klein, Sanja, Onno Kruse, Charlotte Markert, Isabell Tapia León, Jana Strahler le Rudolf Stark.

inahaneloang

Patlisiso ea batho ea neuroimaging e fana ka maikutlo a boteng ba netweke e le ngoe ea mantlha bakeng sa boleng bo ikhethileng ba meputso, ho kenyeletsoa le striatum le orbitofrontal cortex. Leha ho le joalo, ha ho na lipatlisiso tse nyane mabapi le setšoantšo sa neural sa meputso e ikhethang ea litlhahiso tsa thobalano (VSS) le karolo ea litekanyetso tsena tse ikhethileng kholisong ea boits'oaro bo amanang le bona. Mona, re batlisisa hore na neural reactivity ho VSS e hokahane joang le khetho ea motho ka mong ka ho sebelisa litšoantšo tsa magnetic resonance imaging (fMRI). Nakong ea scan ea fMRI, banna ba 72 ba ile ba shebella lifilimi tsa VSS tse fapaneng. Lintlha tse mabapi le valence le ho tsosa takatso ea thobalano li ile tsa bokelloa 'me tsa sebelisoa e le li-modulators tsa parametric tlhahlobisong ea fMRI. Bafo ba ile ba boela ba tlatsa lipotso tsa lipotso ka matšoao a iponahatsang a ho sebelisa litšoantšo tse manyala tse hlephisang boitšoaro (PPU). Taba ea mantlha, re fumane hore li-neural reactivity tse lebisang ho VSS clip ho li-nucleus accumbens, caudate nucleus le orbitofrontal cortex li ne li hokahane hantle le likhahla tsa VSS ka kotloloho lithutong tsohle. Taba ea bobeli, matla a kopano lipakeng tsa ts'ebetso ea methapo le likhahla tsa ho tsosa takatso ea thobalano e ne e tsamaellana hantle le matšoao a ho itlaleha a PPU. Sephetho sa pele se fana ka tekolo e nepahetseng ea VSS ho latela likhetho tsa motho ka mong libakeng tse behiloeng tsa tekolo ea moputso. Taba ea bobeli, phapang e matla ea methapo e thehiloeng ho khetho ho bankakarolo ba nang le matšoao a mangata a PPU e bonts'a bohlokoa bo eketsehileng ba VSS / khetho e loketseng batho bana. Ngollano ena e matlafalitsoeng pakeng tsa motho ka mong ea ratang le ts'ebetso ea methapo e ka nolofalletsa nts'etsopele ea PPU ka ho eketsa ho bonts'a matla a ho hlohlelletsa, ka hona ho matlafatsa tšusumetso ea ho batla le ho arabela tšusumetso ena e ratoang.