Ubume beSakhiwo seBongo. 2013 Nov 16.
Koehler S1, I-Hasselmann E, Wüstenberg T, Heinz A, I-Romanczuk-Seiferth N.
Abstract
Izifundo ezisebenzayo ze-neuroimaging ziye zanyanzelisa ukubandakanyeka kwecortex yangaphambili kunye nenkqubo yomvuzo we-mesolimbic (okt, i-ventral striatum) ekungcakazeni kwe-pathological (PG). Nangona kunjalo, kukho ukunqongophala kwezifundo ezigxila kutshintsho lolwakhiwo kwimimandla yengqondo engaphambili kwizifundo zabantu abadala abane-PG. Ukuze kufundwe umahluko kumthamo wemicimbi yengwevu yengingqi, izifundo ze-20 zamadoda ezine-PG kunye ne-21 yolawulo oluhambelana nazo zenziwe ngendlela yokucinga. Idatha yobuchopho bokwakhiwa yahlalutywa kusetyenziswa i-voxel-based morphometry kugxilwe kwiindawo eziphambili kunye ne-ventral striatum. Ngokuthelekisa imixholo yeengwevu kwimimandla yobuchopho ebaluleke kakhulu kutshintsho olusebenza kwengqondo kwi-PG, uphononongo lwangoku lufumene ivolumu ephezulu kwi-ventral striatum kunye ne-cortex yasekunene yangaphambili ngendlela ye-voxel-Wisdom morphometry kwizifundo ze-PG xa kuthelekiswa nolawulo. Iziphumo zethu zibonisa utshintsho lwengwevu yengingqi kwindawo yobuchopho ebikhe yanxulunyaniswa notshintsho lomsebenzi kwi-PG. Ihypertrophy ekwi-cortex yangaphambili inokuthi ibe yinto ehlengahlengiswayo ubuncinci inkuthazo yomthamo wezinto ezingwevu ezingaphezulu kwi-ventral striatum kwaye inokunceda ukukhulisa ulawulo lokuqonda kwimingcipheko yokungcakaza. Uphando lwexesha elizayo kufuneka luphonononge ubudlelwane phakathi kokusebenza okusebenzayo kunye nolwakhiwo kunye nezifundo kwiinguqu kwi-PG.
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