Physiol Behav. 2018 Aug 1;192:3-16. doi: 10.1016/j.physbeh.2018.04.001.
Spierling SR1, Kreisler AD2, Williams CA2, Fang SY2, Pucci SN2, Kines KT2, UZorrilla EP3.
Abstract
Ukunyanzeliswa kokutya luphawu lokuphazamiseka kokutya kunye ne-bulimia nervosa kwaye kubandakanyeka kwezinye iimeko zokutyeba. Ukuphazamiseka kokutya kuyi-dimorphic ngokwesondo, kwaye abasetyhini bachaphazeleka kaninzi kunamadoda. Iimodeli zezilwanyana zokuzinkcinkca-ezifana nokutya okusekelwe ekufikeleleni okwethutyana ekutyeni okunencasa zikhona; kodwa, kuncinci okwaziwayo malunga neeyantlukwano zesini okanye ukuba sesichengeni komntu kule mifuziselo ngokubhekiselele ekuqiniseni ukusebenza kakuhle kokutya, ukuphuhliswa kokunyanzeliswa- kunye nokutya okufana nokutya, okanye utshintsho oluhambelanayo kwimetabolism yomzimba wonke okanye ukwakheka komzimba. Indoda ebuntwaneni (n = 24) kunye nesetyhini (n = 32) Iigundane ze-Wistar zagcinwa kwi-chow okanye ukutya okukhethiweyo, i-high-sucrose, i-chocolate-flavored diet incontinuous or intermitted, i-external access conditions. Ubunzima bomzimba kunye nokwakheka, ukuthathwa, ukuzilawula okusisigxina kunye nenkqubela-phambili, kunye nenkcitho yamandla omzimba wonke kunye nemilinganiselo yokutshintshiselana ngokuphefumla kulinganiswe kwithuba lokufunda le-11 leveki. Uhlalutyo lweqela eliphantsi lwenziwa ukwahlula isinyanzelo-njengeempuku zofikelelo ezisinyanzelo "eziphezulu" eziye zanyukela ekusebenzeni okugqithisileyo kobume bolawulo lokuzilawula ngokuchasene "nabaphenduli abaphantsi." Amagundane amabhinqa ayenamandla okuqinisa ukutya kunamadoda kuzo zonke iimeko zokutya kwaye ahlala ehlelwa "njengabaphenduli abaphezulu". Kuzo zombini izini, iimpuku ezinokufikelela okwethutyana zibonise ukukhwela ibhayisekile kokusetyenziswa kwe-fuel substrate kunye nenkcitho yamandla wonke. Ngaphaya koko, iimpuku zabasetyhini “eziphendulayo eziphakamileyo” bezinomlinganiselo ophakamileyo wokutshintshiselana ngokuphefumla, nto leyo ebonisa i-phenotype eyonga amanqatha. Izifundo zexesha elizayo ziyafuneka ukuze siqonde ngcono isiseko semolekyuli kunye ne-neurobiological yesini kunye nomahluko ngamnye esiwubonileyo kwiimpuku kunye nefuthe lazo lokuguqulela kubantu abanengxaki yokutya ngokunyanzelekileyo.
IINKCUKACHA: Ukutya okunyanzelekileyo OKANYE ukunyanzeliswa; Inkcitho yamandla OKANYE ubushushu; Umlinganiselo osisigxina kunye neeshedyuli zomlinganiselo oqhubekayo wokuzilawula komntu osebenza ngokutya; Ukukhotyokiswa kokutya OKANYE ukutya okukhobokisayo OKANYE ukutya umlutha; Ubunzima obugqithisileyo OKANYE ukutyeba OKANYE ukutyeba OKANYE ukwakheka komzimba OKANYE amafutha omzimba OKANYE ubunzima bomzimba; Umlinganiselo wotshintshiselwano ngokuphefumla OKANYE umlinganiselo wokuphefumla OKANYE I-RER
PMID: 29654812
PMCID: PMC6019212
DOI: 10.1016 / j.physbeh.2018.04.001
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