Pharmacol Biochem Behav. 2012 Aug;102(2):177-83. doi: 10.1016/j.pbb.2012.04.007. Epub 2012 Epreli 28.
I-Cibrian-Llanderal T1, URosas-Aguilar V, I-Triana-Del Rio R, IPerez CA, UManzo J, IGarcia LI, ICoria-Avila GA.
Abstract
Iimodeli zezilwanyana ziye zabonisa ukuba iziseko ze-neural zokunamathiselwe kwintlalontle, ukhetho lwezesondo kunye neebhondi ezimbini, zixhomekeke kwi-dopamine D2-type receptor kunye nomsebenzi we-oxytocin. Ukongeza, uphononongo lubonise ukuba ukuhlalisana kunokubumba ukhetho lweqabane ngokusebenzisa imeko. Apha, sisebenzise iimpuku ukuphonononga uphuhliso lweendlela ezifundwayo zesini esifanayo nesabantu abadala ngenxa yokuhlalisana ngexesha eliphuculweyo lomsebenzi we-D2. Uvavanyo lwama-Wistar abesilisa (N = 20), bafumana i-saline okanye i-agonist ye-D2 (i-quinpirole) kwaye bavunyelwa ukuba bahlalisane ngexesha le-24 h, kunye neqabane lendoda elikhuthazayo elithwele ivumba le-almond ngasemva njenge-stimulus conditioned. Oku kwaphindwa rhoqo ngeentsuku ezi-4, kwizilingo ezithathu zizonke. Kwiintsuku ezine emva koko baye bavavanywa bengenazo iziyobisi kukhetho lweqabane phakathi kwendoda enevumba elimnandi kunye nebhinqa elamkele ngokwesondo. Ukuthanda iqabane ngesondo kwahlalutywa ngokulinganisa amaxesha amaninzi kunye nokubambezeleka kokuziphatha okukhanukelayo kunye nokuziphatha okugqibeleleyo kwezesondo, kunye nokumiswa okungadibanisiyo. Ukhetho lwentlalo lukwahlalutywa ngokulinganisa amaxesha amaninzi kunye nokubambezeleka kotyelelo, unxibelelwano lomzimba kunye nexesha elichithwe kunye. Iziphumo zibonise ukuba kuphela amadoda aphathwa nge-quinpirole abonise ukhetho lwezesondo kunye nentlalo yoluntu kwindoda enevumba elimnandi ngaphezu kowesifazane owamkelayo ngokwesondo. Bachitha ixesha elininzi kunye, babonisa unxibelelwano lomzimba ngakumbi, ukuziphatha okufana nokwasetyhini, kunye nokwakhiwa okungaphezulu kokunganxibelelani. Ngokufanelekileyo, amadoda akwimeko ethile abonakala evuseleleke ngokwesondo ngakumbi kwaye ekhuthazwa yindoda eyaziwayo kunangowasetyhini owamkelayo. Sixoxa ngeziphumo zalo mzekelo wezilwanyana ekuqulunqweni kwezinto ezikhethwa ngabantu abathandana besini esifanayo.
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