Ingabe i-dopamine receptors ingayibonisa izinkomba zokubheja?
I-Romeo Guinea I-Pig ibangela ingane
Ingulube engu-Guinea ebizwa ngokuthi yi-Sooty ijabulele ubusuku bethandana nabesifazane abangamashumi amabili nane ngemuva kokukhohlisa yaya ekhejini labo eningizimu yeWales. USooty waheha izingulube ze-lady lady, ngamunye ngamunye, futhi manje usebe ngubaba oziqhenyayo wezingulube ezingamashumi amane nambili zezingane. . . . “Ubephatheke kabi impela. Simbuyisele ehokweni lakhe walala izinsuku ezimbili. ”
The I-Coolidge Effect isinqumo esiqinile sebhayoloji sokungashiyi muntu othandana naye ongafakwanga inzalo nganoma iyiphi izindleko. Kuyinto ejwayelekile ezilwaneni ezincelisayo, futhi ibonwe nakwabesifazane, futhi ingalandelwa yonke indlela ibuyele kokwethu izihlobo ezikude: amagundane. Nakuba thina abantu bayizigqila zombili, uhlelo lwethu lokubambisana lusabambisana nalokhu osekhulile ube nethuba-uzothola isisusa.
Yonke yokuziphatha kwezilwane, kuhlanganise ne-Coolidge Effect, isekelwe ekukhuphukeni nasekuweleni kwamakhemikhali e-neurochemical kanye nezinguquko kumamukeli. Ucwaningo lwamuva isikisela ukuthi eminye imishini yokulungisa ubuqhawe bukaSooty ingacathamela i-striatum — iqembu eliyinkimbinkimbi lezakhiwo ezisebenza njengesikhungo esiphakathi semijikelezo yobuchopho. I-striatum ihlotshaniswa nomvuzo nokuzonda, futhi inomthelela omkhulu ezinqumweni zethu. Ubulili, uthando nokuhlangana kuqhubeka kulezi zakhiwo. Uma bengakhanyi, “akwenzeki.”
Isibonelo, izidakamizwa zokuzijabulisa zivame ukugcwala ubuchopho nge-dopamine. Ama-neurons abalulekile ku-striatum asabela ngokuvala ama-receptors amaningi we-D2 (dopamine), aqede okuphezulu. Lokhu kuguqula imizwa yomvuzo nesisusa kuze kube yilapho ubuchopho businda. Zimbalwa izamukeli ze-D2 ezibonakala zisho ukuthi, "Ngidinga i-dopamine eyengeziwe ukuze ngizizwe ngilungile." Isifunda somvuzo sikhala ngokukhuthaza futhi kuphela izinto ezijabulisa kakhulu ezizokwenza. Ubulili, izidakamizwa ne-rock 'n' roll… noma mhlawumbe uHäagen Dazs. Eqinisweni, abasebenzisi bezidakamizwa ezisindayo abane-dopamine receptors esephelile bathambekele ekulahlekelweni intshisekelo kwezocansi nasekuhlanganiseni; badinga ukukhahlela okunamandla. Ama-receptors e-D2 nawo asiza ukubeka amabhuleki ekusetshenzisweni ngokweqile. Ama-receptors ambalwa we-D2 yenza izifiso zikhuni ukumelana.
Kucwaningo olubalulwe ngenhla, ososayensi abafuna ukufunda okwengeziwe ngokudla okudliwayo kubantu babika ezinye ezithokozisayo zokuthola i-dopamine-receptor. Ukudla amakhompi okudla okudliwayo (ama-cheesecake nama-sausage) anciphisa inani le-receptors ye-D2. Kuphi? Ku-striatum. Ngemuva kokuba amagundane adle isidumbu sawo sokugcina sokudla okungaphezulu kwe-yummy, ubukhulu be-receptor babuhlala buphansi okungenani amasonto amabili (ubude bokuhlolwa).
Njengokusetshenziswa kwezidakamizwa zokuzilibazisa, i-striatum yasabela ekukhuliseni okukhulu, kodwa yenza ngendlela ehluke kakhulu ngendlela ephendula ngayo, ethi, i-cocaine. Uma kwenzeka i-cocaine, i-D2 receptor mass ivuselela emuva ezinsukwini ezimbili (nakuba ezinye izinguquko zingase ziqhubeke). Kodwa ngokudla-a zemvelo i-reinforcer (i-buzz) -ukuncipha kwe-D2 kuqhubeka isikhathi eside kakhulu. Kuyathakazelisa ukuthi ukuncipha kuhlala isikhathi eside ngemuva kokudla, kubhekwa ukuthi i-cocaine ibangela ukuqhuma okukhulu kwe-dopamine. Ingabe uhlelo lwezakhi zofuzo luyangena?
Kukhona okunye okwesabekayo okuqhubekayo, futhi. Njengokuqhubeka nokusetshenziswa kwezidakamizwa, ubuchopho bamagundane obhalisiwe injabulo encane ukwenza kusebenze. Futhi kuboniswe ekuziphatheni kwabo ngemuva kokudakwa: i-rat chow ejwayelekile ilahlekelwe yiso sonke isikhalazo. Ukusetshenziswa kuhlala kuphansi kunokujwayelekile amasonto. "I-Cheesecake noma lutho," kubonakala sengathi amagundane ayacabanga. (Ngokuthakazelisayo, ama-opioid akhiqizwa ukusetshenziswa koshukela enza njenge enye indlela yokulwa ne-satiety ngokuphazamisa ukukhiqizwa kwe-oxytocin.)
Ngokusobala, i- “binge trigger” (ngokusebenzisa noma yiziphi izindlela) iyinzuzo yokuziphendukela kwemvelo ezimeni lapho ukusinda kuqhubeka khona ngokuhlanganyela ekuziphatheni sidlulile iphuzu lokuphumula okujwayelekile. Cabanga ngebhere eligcwala ama-salmon anamafutha amaningi ngaphambi kokulala. Noma izimpisi, ezidinga ukubeka kude kuze kufike kumakhilogremu angamashumi amabili wokubulala okukodwa ngasikhathi sinye. Noma okhokho bethu, ababedinga ukugcina amakhalori asezingeni eliphakeme njengamakhilogremu ambalwa wokuhambisa okulula ukusinda ezikhathini ezinzima. Noma wena uma ugcwele i-turkey namazambane acubuziwe bese kuvela uphayi wakho wokubonga owuthandayo.
Uma ubuchopho bethu bokuqala buzwa into ethize iwusizo ngempela, lifuna sisebenzise ithuba legolide… ngokugcwele. Angeke ikwenze lokho ngemizwa efudumele, engenangqondo yokwaneliseka. Cha. Kufanele yakhe imizwa ye- ukuntuleka or ukunganeliseki (izifiso) ukuze kusishukumisele ukuba sidlule imingcele yethu evamile.
Izinguquko ezibalulekile kuma-receptors zisenza sizizwe sengathi okuthile… akulungile. Sifuna ukuzizwa kahle futhi, noma yini edingekayo. Akuyona yonke into ezosenzela thina, noma. Ngeke silunge evamile, ngoba ubuchopho bethu bufuna ukuthi sigxile kokuhle kakhulu… kuphela. Amazinga ajwayelekile we-dopamine akwanele. Siba ngabafuna ngenkani. Sifuna okuthile okweqile, into ebhalisa "njengenani eliphakeme" (noma ngabe liyilo noma cha), into ezoqala ukukhishwa kwe-dopamine (nempendulo yenjabulo) ubuchopho bethu manje sebufisa. I-Dopamine ikhishwa lapho okuthile kungcono kunokulindelekile, futhi i-spike ye-dopamine izoshukumisa ama-receptors ambalwa asele ku-striatum ukusinikeza okunye ukunambitheka kwemizwa emihle… ngaphambi kokuba sizizwe singanelisekile futhi.
Hlala wazi ukuthi umsebenzi wesekethe wokuthola umvuzo ukuhlala unganelisekile kancane nangaphansi kwezimo ezinhle kakhulu. Ngale ndlela, sihlonyelwe ukusebenzisa amathuba athembisayo, noma sibheke phambili ngentshiseko ekuthokoziseni okuhlehlisiwe kwempumelelo, ukuqomisana okuphumelelayo noma ukonga ukwandisa izinketho zesikhathi esizayo.
Imvamisa lesi sici sokwenza kwethu sisinikeza isifiso sokuphila nokufeza okuthile. Kepha uma sivuselela ngokweqile futhi singanaki imijikelezo yethu, izinjabulo ezijwayelekile nezinhlelo zokuvelela ngekusasa azinikezi i-buzz ejwayelekile. Okubi kakhulu ukuthi, kungenzeka singabazisi ubudlelwano nothando olufudumele thina esizweni, izimpungushe ezibophezelayo ezizidinga ngomuzwa wenhlalakahle. Esikhundleni salokho, kungenzeka sizizwe singenelisekile neze — ngisho nabathandekayo bethu — futhi siqinisekile ukuthi kukhona iphutha abalitholayo ngokungazanelisi izidingo zethu ezihaba. Sifuna ukwaneliseka ngokushesha, noma ngabe sibeka engcupheni imigomo yethu yesikhathi esizayo. Izakhi zethu zofuzo zisidonse ngendlebe ngempumelelo yethu ngezinjongo zabo.
Kungenzeka ukuthi ukuqonda okungcono ukuthi indlela yokuvuselela i-super-stimulation iguqule kanjani ukuxhuma kwabantu kusiza abantu ukuba baqonde ukuthi i-65% yamaMelika ayinamandla kakhulu futhi amadoda anamakhompyutha atholakala kuyo yonke indawo athola i-Internet riveting? Ingabe sisuke sinyatheliswa ngama-receptors aphansi e-D2 nezinye izinguquko eziphathelene nobuchopho ezibangelwa yilo, ngabe ngabe kwabayikho bethu, ukuvuselela okungavamile ngempela?
Cabanga ngoSooty ebamba ithuba lakhe lokuya enkantolo yabesifazane bakhe. Noma ukuvuma umculi uJohn Mayer ukuthi manje ikhetha amahora we-porn ebudlelwaneni nabesifazane bangempela. (Futhi yebo, abesifazane bazitika kakhulu nge- "khekhe" futhi. Bona (umculi) 'UKaty Perry weqa ukusebenza ukuze abuke izithombe ezingcolile!')
Isibonakaliso se-gadfly ebuchosheni sibe yindleko enobungozi lapho ukudla okunamnandi kakhulu noma amaqabane amasha angakhuthaza atholakalayo ukunikezela okungapheli. Lapho i-trigger yokudla isalokhu isebenza, ukwaneliseka kuyasibalekela noma ngabe sidla noma sithola okungakanani ukukhuthazeka. Okuxakayo-ke ukuthi uma umuntu ezithola efuna isikhuthazo esishisayo nesishisayo, akukhona ukuthi uthola injabulo ethe xaxa, kodwa ngoba uthola Ngaphansi. Ukuphefumula komoya kuyakhazimula kowesifazane ominzayo ngoba umoya-mpilo wakhe uphansi. Ngokufanayo, ubuchopho obundindizelwe budinga lokho okungenakho — ukuvuselelwa okujabulisayo — ngoba ukuzwela okuvamile kuyehla. Isifiso esikhuthele sokufuna injabulo kalula singaphanjaniswa nenjabulo, noma ngabe empeleni kunzima isithembiso wenjabulo.
Amagundane akulesi sifundo asheshe akhuluphala lapho enikezwa amanani angenamkhawulo we-extravagancies. Ngokungafani namagundane ajwayelekile, awazange abeke phansi okukhona ngisho nalapho esongelwa ngogesi. Badla ngokweqile okungenampilo; babenganeliseki. Cabanga imilutha yezidakamizwa.
Ngabe abasebenzisi be-porn balwa nalesi sifo sokudakwa esifanayo ku-striatum lapho bengakwazi ukuthola okwanele "abashade" abasha abavusa inkomba ngokuchofoza ngakunye? USooty uthole ukuphumula okudingeka kakhulu ngemuva kokuhlangana nekheji eligcwele abesifazane, kepha umsebenzi womsebenzisi we-porn ungalokothi kwenziwe. Kuhlala kunomunye “umlingani” obubula ngokubuka. Ubuchopho bethu busidonsela ukuba sihlale emsebenzini lapho izinto ziningi. Kubukeka sengathi kunokuthile okuhlukile ngokuphendula kwengqondo yethu ekudleni okulingayo kakhulu nasekuvuseleleni ngokocansi.
Kungenzeka futhi ukuthi uma i-orgasm inganikelanga uhla olugcwele lokuthoba ukuziphatha okuzibophezelayo (njengoba ku ubulili ngaphandle komlingani), sisengozini enkulu yokuzizwa singanelisekile kungekudala nje. Ngemuva kwakho konke, ngokubuka kofuzo lwethu, umsebenzi wethu wokukhulelwa awenziwa. Uma kunjalo, ingabe lokhu kuphakama kuyi-libido yangempela — noma ukunganeliseki okwenziwe ngenxa yokushintsha kobuchopho okunciphisa imizwa yokwaneliseka?
Kungenzeka yini ukuthi noma i-orgasm eyodwa kwesinye isikhathi ikhuphule izifiso ezilandelayo? Akekho owazi ngokweqiniso. Kodwa-ke, ukuminyana kwegundane le-dopamine receptor kwehla kakhulu ngosizo lwayo lokuqala lwasezulwini lokudla okunamafutha. Kubukeka sengathi kukhona ukugqagqana ku-binge trigger okushayela kokubili ukukhwelana nokudla. Ukuthola abasebenzisi be-porn bathola ukuthi ukudla ukudla okungenamsoco kukhulisa izifiso ze-porn ngesikhathi sokuhoxa. Futhi mhlawumbe uzwile lelo hlaya elidumile mayelana nentombi ekahle, ephenduka ibe yi-pizza phakathi kwamabili.
I-neurochemistry ye-orgasm nokudla ngokuqinisekile akunakuncishiselwa kuzinguquko ze-D2-receptor. Kodwa-ke, izinguquko ze-receptor zingaba yingxenye yephazili lokuthi kungani kwesinye isikhathi isifiso sobulili sikhula ngaphandle kokunikeza ukwaneliseka okuhlala njalo. (Uma umqondo wokulibala ukujikeleza emva kwe-orgasm kuyinto entsha kuwe, ungase ujabule ukwazi ukuthi ucwaningo seluvele lwembula umjikelezo okungenani izinsuku eziyisikhombisa kumadoda.)
Mhlawumbe ucwaningo ngolunye usuku luyohlinzeka ngemephu yomgwaqo yokushintsha kobuchopho ngemuva kwezenzo ezahlukahlukene zocansi. Lapho-ke ngeke sishiyelwe kuphela emuseni wezingcindezi zobuchopho bethu ekufuneni ukwaneliseka.
Izibuyekezo:
- 2019 - Emagundeni, ukudla okunamafutha aphezulu kunciphisa 'u-brake' osetshenziselwa ukulawula ukudla
- 2016 - Abacwaningi bavula indlela ebuchosheni obuhlukanisa ukudla nokuzifiso
- 2015 - I-Dopamine Surge May Lingachaza Ukudla Kwakho Okudlayo: I-Insulini Ebonakalayo Ukuze Yisebenze Izimpawu Zomvuzo Embukilini Wakho
- 2010 - Izibalo Emazweni Aphezulu Kakhulu Emhlabeni
Okuningi ekucwaningweni okuyinhloko:
Kuchazwe umcwaningi uPaul Kenny, ubuchopho bukhipha i-dopamine ekuphenduleni kokuhlangenwe nakho okujabulisayo njengokudla ikhekhe, ukwenza ucansi noma ukukhipha i-cocaine. Kepha, injabulo enkulu isusa izindlela zomvuzo wobuchopho ngokweqisa i-receptor ye-D2 futhi ibangele ukuthi icishe. Kumagundane ayimilutha yokudla okungenamsoco, okuwukuphela kwendlela yokuvuselela izikhungo zabo zenjabulo kwakuwukudla ukudla okunamafutha aphezulu kakhulu, okunama-khalori amaningi. "Abatholi imivuzo ngendlela obekufanele ngayo," kusho uKenny.
OKUSHA: Kungani kunzima kangaka ekudleni (Ucwaningo lwamaTufts luqinisekisa ukuthi "izilwane ezikhuluphele kakhulu nezingaphansi kwesisindo zombili" zinokusilela okufana ncamashi ebuchosheni — ukuntuleka okuphawulekayo kwe-dopamine ekhishwe kusayithi elixhumanisa umvuzo. "
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