I-CNS Spectr. I-2015 Dec; 20 (6): 557-65. doi: 10.1017 / S1092852915000814.
I-Balodis IM1, I-Grilo CM1, Potenza MN1.
abstract
Izici zokuphathwa kwe-biobehaisheral ezihambisana nokuphazamiseka kokudla i-binge (BED) ziye zaphenywa; noma kunjalo, ukubuyekezwa okumbalwa okuhlelekile kuze kube manje okuchaze okutholakele kwe-neuroimaging kusuka kwizifundo ze-BED. Izifundo ezisebenzayo nezihlelekile zisekela i-BED njengezici ze-neural ezihlukile nezindizayo njengoba ziqhathaniswa nokunye ukuphazamiseka. Izifundo ze-Neuroimaging zinikeza ubufakazi obuxhumanisa izimpendulo ezikhulayo ezinkambeni zokudla ezifinyeleleka kalula nezindawo ezisetshenziswayo, ikakhulukazi i-orbitof Pambal cortex (OFC), nobudlelwano obuthile nezindlela zokuzwa indlala nokuzwela umvuzo. Ngenkathi izifundo ezimbalwa kuze kube manje ziye zaphenya izimpendulo ezingezona zokudla; lokhu kusikisela i-hypofunctioning ejwayelekile ezindaweni ezingaphambili ngesikhathi senkokhelo nezinqubo zokulawula i-inhibitory. Izifundo zakuqala ezisebenzisa i-neuroimaging emizamweni yokwelashwa zibonisa ukuthi ukuqondisa ukusebenza kwe-neural ngaphansi kwezinqubo ezigqugquzelayo kungabonakala kubalulekile ekwelashweni kwe-BED.
KEYWORDS:
Ukuphazamiseka kokudla; izinkomba zokudla; i-neuroimaging; ukukhuluphala; i-cortex ejikelezayo; ukucubungula ngomvuzo; i-ventral striatu
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