Umsebenzi Wobuchopho Bct. 2013 Nov 16.
Koehler S1, I-Hasselmann E, Wüstenberg T, Heinz A, I-Romanczuk-Seiferth N.
abstract
Izifundo ezisebenzayo ze-neuroimaging zifake umfutho ekubandakanyekeni kwe-preortal cortex ne-mesolimbicomvu system (ie, i-ventral striatum) ekugembeni kwe-pathological (PG). Kodwa-ke, kunokuntuleka kwezifundo kugxile ekushintsheni kwesakhiwo ezifundeni zobuchopho be-frontostriatal ezifundweni zabantu abadala ezine-PG. Ukuze utadishe umehluko ngevolumu yendawo yengwevu yendawo, izihloko zesilisa ze-20 ezine-PG ne-21 zokulawulwa zifaniswe ngaphansi kokucatshangwa kokuhlelwa kobuhlakani bezakhiwo. Idatha yobuchopho yokwakheka ihlaziywe nge-voxel-based morphometry kugxilwe ezindaweni ezingaphambili kanye ne-ventral striatum. Ngokuqhathanisa ivolumu ye-grey nkhani ezifundeni zobuchopho ezifanele kakhulu ekushintsheni kokusebenza kwengqondo ku-PG, lolu cwaningo lwamanje luthola inani eliphakeme ku-ventral striatum kanye ne-cortex yesokudla yangaphambili nge-voxel-Wisdom morphometry ngezihloko ze-PG ngokuqhathaniswa nezilawuli. Ukuthola kwethu kukhombisa ushintsho lwendabuko yendawo ezindaweni zobuchopho ezihlotshaniswe ngaphambili nezinguquko ezisebenzayo ku-PG. I-Hypertrophy ku-cortex yangaphambili ingahle ibe yinto ethathelwa phezulu kancane kancane ivuswe yivolumu ephezulu yempunga ku-ventral striatum futhi ingasiza ukukhulisa ukulawulwa kwengqondo ngokuthambekela kokugembula. Ucwaningo lwekusasa kufanele luhlolisise ubudlelwane phakathi kwezinguquko ezisebenzayo nezihlelekile kanye nenkambo yezinguquko kwi-PG.
;