Unyaka : 2011 | ivolumu : 6 | Issue : 26 | ikhasi : 2037-2041
I-Ling Ge1, I-Xiuchun Ge2, Yong Xu3, UKerang Zhang3, Jing Zhao4, I-Xin Kong4 1 Umnyango Wezokwelapha Ngokwelapha, I-Shanxi Medical College yokuqhubeka nemfundo, iTayyuan 030012, iPhrovinsi yaseShanxi, eChina
2 I-Shanxi Hospital Hospital, i-Taiyuan 030024, iPhrovinsi yaseShanxi, eChina
3 UMnyango Wezokwelapha, Isibhedlela Sokuqala se-Shanxi Medical University, iTayyuan 030001, iPhrovinsi yeShanxi, eChina
4 College of Humanities kanye neSayensi Yezenhlalakahle, i-Shanxi Medical University, iTayyuan 030001, iPhrovinsi yeShanxi, eChina
LINKA KU-ABSTACT
Imiphumela yophenyo lwamanje lwe-ERP kubantu abathintekayo ku-IAD behambisana nokufundwa kwezifundo zangaphambilini zezinye izidakamizwa [17-20]. Ngokuqondile, sithole ubukhulu be-P300 namaphesenti angu-P300 latency kumuntu ngamunye obonisa ukuziphatha okuluthayo uma kuqhathaniswa nokulawula okunempilo. Le miphumela isekela ukucabangela ukuthi izindlela ezifanayo zomzimba zihileleka ekuziphatheni okuhlukene kwezidakamizwa.
KUPHELA
Imiphumela yophenyo lwamanje lwe-ERP kubantu abathintekayo ku-IAD behambisana nokufundwa kwezifundo zangaphambilini zezinye izidakamizwa [17-20]. Ngokuqondile, sithole ubukhulu be-P300 namaphesenti angu-P300 latency kumuntu ngamunye obonisa ukuziphatha okuluthayo uma kuqhathaniswa nokulawula okunempilo. Le miphumela isekela ukucabangela ukuthi izindlela ezifanayo zomzimba zihileleka ekuziphatheni okuhlukene kwezidakamizwa.
Izifundo eziningana zangaphambilini zigxile ekuhlanganiseni phakathi kwe-IAD ne-P300, ukubika okunciphiswe kwe-P300 amplitudes [11, 20]. Ngokuphambene nalokho, asizange sibone ukunciphisa okuphawulekayo kwe-P300 esifundweni samanje. Kodwa-ke, sithole ukuthi i-P300 latency ende ihlanganiswe ne-IAD, ehambisana nesifundo esisodwa sangaphambilini [20]. Nakuba iziphetho ezicacile azikwazi ukudonsa mayelana nokungafani kwamaplitude we-P300, usayizi wesampula namandla okubala kungenzeka ukuthi wadlala indima enkulu. Ucwaningo lwamanje luhlolisise usayizi wesampula omkhulu kakhulu (n = 38), ukuqashelwa okuhlelekile kanye nenqubo eqondile yokuxoshwa kokuthola i-IAD. Ukutholakala kwamanje kungahle kube nokwethenjelwa ngokweqile kunalokho okufundiswa kwangaphambilini, kodwa kufanele kuhunyushwe ngokucophelela. Ngakolunye uhlangothi, iminyaka yabahlanganyeli kungenzeka nokuthi nayo ithinte imiphumela. Bonke abantu abasesampula sethu babesilisa abaneminyaka eyiphakathi (iminyaka yobudala yabahlanganyeli be-IAD: iminyaka engu-32.5 ± 3.2; kusho iminyaka yobudala: iminyaka engu-31.3 ± 10.5), kanti isampula esincane esincane sasihlolwe esifundweni sangaphambilini sika Yu et al [11] (iminyaka yobudala yezihloko ze-IAD: 22.0 ± 0.9 iminyaka; kusho iminyaka yobudala: iminyaka engu-22.0 ± 0.7). Kungenzeka ukuthi ukunikezwa kwemithombo yokwaziswa okucabangayo kubaluleke kakhulu ekuthuthukiseni i-IAD kubantu asebekhulile kuqhathaniswa nabantu abasha.
Okunye okutholayo okukhulu kwalolu cwaningo lwukuthi ukuqala kwesikhathi eside kwe-P300 kubantu abane-IAD kwehlile kakhulu ngemuva kwe-CBT. Uma sicabangela ukungabi khona kwezifundo ku-IAD kubandakanya ukwelashwa nokulandelwa kwezinyathelo, inhlangano phakathi kweP300 latency kanye ne-IAD ukwelashwa kwisampula sethu kufanele ihunyushelwe ngokucophelela. Ucwaningo oluqhubekayo kufanele luqhutshwe ukuze luphindaphindiwe lokhu kutholakala, besebenzisa izinhlobo zesampula ezinkulu kanye nezinye izinhlobo zokwelashwa. I-P300 latency ibhekwa ukuthi inikeza isilinganiso esithile sokwabiwa kwezibonelelo [21], nokukhuliswa kwalesi sigaba se-ERP kukhulunywe njengengqikithi yezinqubo ezithintekayo ezithinta ubukhulu be-callosal kanye nokusebenza kahle kokudluliselwa kwe-intermedium [22-23]. Okutholakele okwamanje kuphakamisa ukuthi abantu abane-IAD bangase babe nezinkinga ngejubane lokubona kanye nokucubungula kwengqondo ye-stimuli yokuhlola. Ngenxa yokwaziswa okulinganiselwe mayelana nokusebenza kwengqondo ku-IAD, okwamanje kunzima ukukhomba izindlela ezikhona ezibangelwa umphumela we-P300 latency.
Ucwaningo lwangaphambili lubike ukuthi i-P3 imelela umndeni wezingxenye ezihlobene kodwa ezihlukanisekayo ezifaka phakathi "I-Novelty" P3a kanye ne- "Target" P3b [24-25]. I-P3a imele impendulo yokuzenzakalela yokuzenzakalela kumanoveli noma okunye okunamandla okusebenzayo [24, 26]. I-P3b ivame ukuhlotshaniswa nokuzikhethela ngokuzithandela kanye nokubuyekezwa kokukhumbula inkumbulo [27]. Esifundweni samanje, ukuhlanganiswa akutholakalanga kuphela phakathi kwe-P3a ne-P3b latency ne-IAD, kodwa futhi nomphumela we-CBT. Ngokuphambene, akukho izinhlangano ezitholakale zinezingxenye ze-N1 ne-P2. Ngenkathi ingxenye ye-N2 ingahambisani nemiphumela ye-CBT, yayihlotshaniswa ne-IAD. Ukuhlanganiswa, lezi zithole zibonise ukuthi ukulahleka komsebenzi wokuqondisisa okuhlobene ne-IAD akuhlobene nokukhethwa nokunakekelwa kwe-novel (N1 ne-P2). Kunalokho, i-IAD ibonakala ifaka izimpendulo kumsebenzi wenqubo yombhalo (P3a), inkumbulo yokusebenza (P3b) nokuqaphela okuqaphelayo (N2). Ngaphezu kwalokho, ingxenye yomsebenzi wokuziqonda ingathuthuka ngokungenelela kwengqondo yesikhashana. Lezi ziqalo zokuqala zicatshangelwa ngokucacile njengamanje futhi zidinga ukuqinisekiswa okuqhubekayo kwizifundo ezizayo.
Ngokufingqa, i-latency ye-P300 ende yatholakala ukuthi ihlotshaniswa ne-IAD. Lokhu kwesikhashana kwe-P300 latency kwehlile emazingeni avamile ngemuva kohlelo lwezinyanga ezintathu ze-CBT. Lokhu okutholakele kubonisa ukuthi ukulahleka komsebenzi wokucabangela kungabandakanyeka ku-IAD, nokuthi lezi zingathuthukiswa ngokuphathwa kokwelashwa kwengqondo. Ucwaningo oluqhubekayo oluhlolisisa le nhlangano luyadingeka ukuze kuphinde lwenze lokhu kutholakala ngamasampuli ehlukile ubudala, nangokwesayizi omkhulu wesampula.
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