Neuropsychopharmacology. 2012 Ọkt; 37 (11): 2405-15 . doi: 10.1038/npp.2012.97. Epub 2012 Jun 13.
Radke AK, Gewirtz JC.
Source
Mmemme gụsịrị akwụkwọ na Neuroscience, Minneapolis, MN, USA.
nkịtị
Ọtụtụ akara ngosi na-egosi na mgbaàmà mmetụta mmetụta uche na-adịghị mma nke ịwepu gụnyere mbelata ọrụ na sistemụ mesolimbic dopamine. Ọmụmụ ihe a nyochara ntinye aka nke akara ngosi dopaminergic n'ụdị dị n'okpuru mpaghara ventral tegmental iji wepụ ya na mkpughe morphine dị ukwuu, tụrụ dị ka ike nke mmetụ startle reflex. Nlekọta sistemu nke mkpokọta dopamine receptor agonist apomorphine ma ọ bụ mmanya nke D1-dị ka agonist receptor SKF82958 na D2-dị ka onye na-anabata agonist quinpirole na-ebelata ike n'oge mwepu morphine. a emeghariri mmetụta site na ntinye apomorphine n'ime shea nke nucleus accumbens. N'ikpeazụ, egosiri ịgba ọgwụ apomorphine iji belata ike mmalite n'oge mwepu nicotine na enweghị ọnọdụ ịkpọasị na mwepụ morphine. Nsonaazụ ndị a na-egosi na ịgbalite ngwa ngwa nke ventral tegmental mesolimbic dopamine sistemu na-akpalite ngosipụta nke nchegbu na ịkpọasị n'oge mwepu na ọtụtụ klas nke ọgwụ ọjọọ eme ihe.
Neuropsychopharmacology aga n'ihu mbipụta n'ịntanetị, 13 Juun 2012; doi:10.1038/npp.2012.97.
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